Wearable-Sensor-Based Weakly Supervised Parkinson's Disease Assessment with Data Augmentation

Parkinson's disease (PD) is the second most prevalent dementia in the world. Wearable technology has been useful in the computer-aided diagnosis and long-term monitoring of PD in recent years. The fundamental issue remains how to assess the severity of PD using wearable devices in an efficient and accurate manner. However, in the real-world free-living environment, there are two difficult issues, poor annotation and class imbalance, both of which could potentially impede the automatic assessment of PD. To address these challenges, we propose a novel framework for assessing the severity of PD patient's in a free-living environment. Specifically, we use clustering methods to learn latent categories from the same activities, while latent Dirichlet allocation (LDA) topic models are utilized to capture latent features from multiple activities. Then, to mitigate the impact of data imbalance, we augment bag-level data while retaining key instance prototypes. To comprehensively demonstrate the efficacy of our proposed framework, we collected a dataset containing wearable-sensor signals from 83 individuals in real-life free-living conditions. The experimental results show that our framework achieves an astounding 73.48% accuracy in the fine-grained (normal, mild, moderate, severe) classification of PD severity based on hand movements. Overall, this study contributes to more accurate PD self-diagnosis in the wild, allowing doctors to provide remote drug intervention guidance.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:24

Enthalten in:

Sensors (Basel, Switzerland) - 24(2024), 4 vom: 12. Feb.

Sprache:

Englisch

Beteiligte Personen:

Yue, Peng [VerfasserIn]
Li, Ziheng [VerfasserIn]
Zhou, Menghui [VerfasserIn]
Wang, Xulong [VerfasserIn]
Yang, Po [VerfasserIn]

Links:

Volltext

Themen:

Activity recognition
Class imbalance
Data augmentation
Journal Article
Parkinson’s disease
Weak annotation
Wearable sensor

Anmerkungen:

Date Completed 26.02.2024

Date Revised 27.02.2024

published: Electronic

Citation Status MEDLINE

doi:

10.3390/s24041196

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM368903370