Cardiovascular Biomarkers in Cardio-Oncology : Antineoplastic Drug Cardiotoxicity and Beyond

Serum biomarkers represent a reproducible, sensitive, minimally invasive and inexpensive method to explore possible adverse cardiovascular effects of antineoplastic treatments. They are useful tools in risk stratification, the early detection of cardiotoxicity and the follow-up and prognostic assessment of cancer patients. In this literature review, we aim at describing the current state of knowledge on the meaning and the usefulness of cardiovascular biomarkers in patients with cancer; analyzing the intricate relationship between cancer and cardiovascular disease (especially HF) and how this affects cardiovascular and tumor biomarkers; exploring the role of cardiovascular biomarkers in the risk stratification and in the identification of chemotherapy-induced cardiotoxicity; and providing a summary of the novel potential biomarkers in this clinical setting.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:14

Enthalten in:

Biomolecules - 14(2024), 2 vom: 07. Feb.

Sprache:

Englisch

Beteiligte Personen:

Attanasio, Umberto [VerfasserIn]
Di Sarro, Elena [VerfasserIn]
Tricarico, Lucia [VerfasserIn]
Di Lisi, Daniela [VerfasserIn]
Armentaro, Giuseppe [VerfasserIn]
Miceli, Sofia [VerfasserIn]
Fioretti, Francesco [VerfasserIn]
Deidda, Martino [VerfasserIn]
Correale, Michele [VerfasserIn]
Novo, Giuseppina [VerfasserIn]
Sciacqua, Angela [VerfasserIn]
Nodari, Savina [VerfasserIn]
Cadeddu, Christian [VerfasserIn]
Tocchetti, Carlo Gabriele [VerfasserIn]
Palazzuoli, Alberto [VerfasserIn]
Mercurio, Valentina [VerfasserIn]

Links:

Volltext

Themen:

Antineoplastic Agents
Biomarkers
Biomarkers, Tumor
Cancer
Cardiac dysfunction
Cardiotoxicity
Heart failure
Journal Article
Multiple myeloma
Natriuretic peptides
Omics science
Review
Troponin

Anmerkungen:

Date Completed 26.02.2024

Date Revised 27.02.2024

published: Electronic

Citation Status MEDLINE

doi:

10.3390/biom14020199

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM368874214