Night shift work was associated with functional outcomes in acute ischemic stroke patients treated with endovascular thrombectomy
© 2024 The Authors..
Objective: This study aimed to explore the impact of late night shift work on the functional outcomes of patients with acute ischemic stroke (AIS) treated with endovascular thrombectomy (EVT).
Methods: Consecutive AIS patients who underwent EVT between June 2019 and June 2021 were enrolled and divided into non-night shift work and night shift work groups based on their occupational histories. The primary outcome was the modified Rankin Scale score defined 3-month functional outcome. The secondary outcomes were 3-month mortality, symptomatic intracerebral hemorrhage (sICH), ICH and early recanalization.
Results: A total of 285 patients were enrolled, 35 patients (12.3%) were night shift workers, who were younger (P < 0.001) and had a significantly higher prevalence of smoking (P < 0.001), hyperlipidemia (P = 0.002), coronary heart disease (P = 0.031), and atrial fibrillation (P < 0.001). The 3-month favorable outcomes were achieved in 44.8% and 25.7% of patients in the non-night shift work and night shift work groups, respectively (adjusted odds ratio [OR]: 0.24, 95% CI: 0.10-0.57; adjusted P = 0.001). No difference was found in 3-month mortality (adjusted OR: 0.43; 95% CI: 0.14-1.25, adjusted P = 0.121), rates of ICH (adjusted OR: 0.73; 95% CI: 0.33-1.60; adjusted P = 0.430), sICH (adjusted OR: 0.75; 95% CI: 0.34-1.67; adjusted P = 0.487), or early successful recanalization (adjusted OR: 0.42; 95% CI: 0.12-1.56; adjusted P = 0.197). These results were consistent after PSM analysis.
Conclusion: Our findings suggest that late night shift work is significantly associated with unfavorable outcomes in patients with AIS after EVT.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
Heliyon - 10(2024), 4 vom: 29. Feb., Seite e25916 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yu, Wantong [VerfasserIn] |
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| Links: |
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| Themen: |
Endovascular therapy |
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| Anmerkungen: |
Date Revised 24.02.2024 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.heliyon.2024.e25916 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM368801446 |
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| 100 | 1 | |a Yu, Wantong |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Night shift work was associated with functional outcomes in acute ischemic stroke patients treated with endovascular thrombectomy |
| 264 | 1 | |c 2024 | |
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| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © 2024 The Authors. | ||
| 520 | |a Objective: This study aimed to explore the impact of late night shift work on the functional outcomes of patients with acute ischemic stroke (AIS) treated with endovascular thrombectomy (EVT) | ||
| 520 | |a Methods: Consecutive AIS patients who underwent EVT between June 2019 and June 2021 were enrolled and divided into non-night shift work and night shift work groups based on their occupational histories. The primary outcome was the modified Rankin Scale score defined 3-month functional outcome. The secondary outcomes were 3-month mortality, symptomatic intracerebral hemorrhage (sICH), ICH and early recanalization | ||
| 520 | |a Results: A total of 285 patients were enrolled, 35 patients (12.3%) were night shift workers, who were younger (P < 0.001) and had a significantly higher prevalence of smoking (P < 0.001), hyperlipidemia (P = 0.002), coronary heart disease (P = 0.031), and atrial fibrillation (P < 0.001). The 3-month favorable outcomes were achieved in 44.8% and 25.7% of patients in the non-night shift work and night shift work groups, respectively (adjusted odds ratio [OR]: 0.24, 95% CI: 0.10-0.57; adjusted P = 0.001). No difference was found in 3-month mortality (adjusted OR: 0.43; 95% CI: 0.14-1.25, adjusted P = 0.121), rates of ICH (adjusted OR: 0.73; 95% CI: 0.33-1.60; adjusted P = 0.430), sICH (adjusted OR: 0.75; 95% CI: 0.34-1.67; adjusted P = 0.487), or early successful recanalization (adjusted OR: 0.42; 95% CI: 0.12-1.56; adjusted P = 0.197). These results were consistent after PSM analysis | ||
| 520 | |a Conclusion: Our findings suggest that late night shift work is significantly associated with unfavorable outcomes in patients with AIS after EVT | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Endovascular therapy | |
| 650 | 4 | |a Functional outcome | |
| 650 | 4 | |a Ischemic stroke | |
| 650 | 4 | |a Night shift work | |
| 700 | 1 | |a Ma, Jin |e verfasserin |4 aut | |
| 700 | 1 | |a Guo, Wenting |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Jiali |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Sijie |e verfasserin |4 aut | |
| 700 | 1 | |a Ren, Changhong |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Longfei |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Chuanjie |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Chuanhui |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Jian |e verfasserin |4 aut | |
| 700 | 1 | |a Duan, Jiangang |e verfasserin |4 aut | |
| 700 | 1 | |a Ma, Qingfeng |e verfasserin |4 aut | |
| 700 | 1 | |a Song, Haiqing |e verfasserin |4 aut | |
| 700 | 1 | |a Zhao, Wenbo |e verfasserin |4 aut | |
| 700 | 1 | |a Ji, Xunming |e verfasserin |4 aut | |
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