Recent Advances in Management of Neuropathic, Nociceptive, and Chronic Pain : A Narrative Review with Focus on Nanomedicine, Gene Therapy, Stem Cell Therapy, and Newer Therapeutic Options

© 2024. The Author(s)..

PURPOSE OF REVIEW: This manuscript summarizes novel clinical and interventional approaches in the management of chronic, nociceptive, and neuropathic pain.

RECENT FINDINGS: Pain can be defined as a feeling of physical or emotional distress caused by an external stimulus. Pain can be grouped into distinct types according to characteristics including neuropathic pain, which is a pain caused by disease or lesion in the sensory nervous system; nociceptive pain, which is pain that can be sharp, aching, or throbbing and is caused by injury to bodily tissues; and chronic pain, which is long lasting or persisting beyond 6 months. With improved understanding of different signaling systems for pain in recent years, there has been an upscale of methods of analgesia to counteract these pathological processes. Novel treatment methods such as use of cannabinoids, stem cells, gene therapy, nanoparticles, monoclonal antibodies, and platelet-rich plasma have played a significant role in improved strategies for therapeutic interventions. Although many management options appear to be promising, extensive additional clinical research is warranted to determine best practice strategies in the future for clinicians.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Current pain and headache reports - (2024) vom: 22. Feb.

Sprache:

Englisch

Beteiligte Personen:

Kataria, Saurabh [VerfasserIn]
Patel, Utsav [VerfasserIn]
Yabut, Kevin [VerfasserIn]
Patel, Jayshil [VerfasserIn]
Patel, Rajkumar [VerfasserIn]
Patel, Savan [VerfasserIn]
Wijaya, Jeremiah Hilkiah [VerfasserIn]
Maniyar, Pankti [VerfasserIn]
Karki, Yukti [VerfasserIn]
Makrani, Moinulhaq P [VerfasserIn]
Viswanath, Omar [VerfasserIn]
Kaye, Alan D [VerfasserIn]

Links:

Volltext

Themen:

Cannabinoids
Chronic pain
Gene therapy
Journal Article
Nanomedicine
Neuromodulation
Neuropathic pain
Nociceptive pain
Platelet-rich plasma
Review
Stem cells

Anmerkungen:

Date Revised 22.02.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.1007/s11916-024-01227-5

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM368762548