Details der Publikation - Use of the pRESET LITE thrombectomy device in combined approach for medium vessel occlusions

Use of the pRESET LITE thrombectomy device in combined approach for medium vessel occlusions : A multicenter evaluation

© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature..

PURPOSE: Our purpose was to assess the efficacy and safety of the pRESET LITE stent retriever (Phenox, Bochum, Germany), designed for medium vessel occlusion (MeVO) in acute ischemic stroke (AIS) patients with a primary MeVO.

METHODS: We performed a retrospective analysis of the MAD MT Consortium, an integration of prospectively maintained databases at 37 academic institutions in Europe, North America, and Asia, of AIS patients who underwent mechanical thrombectomy with the pRESET LITE stent retriever for a primary MeVO. We subcategorized occlusions into proximal MeVOs (segments A1, M2, and P1) vs. distal MeVOs/DMVO (segments A2, M3-M4, and P2). We reviewed patient and procedural characteristics, as well as angiographic and clinical outcomes.

RESULTS: Between September 2016 and December 2021, 227 patients were included (50% female, median age 78 [65-84] years), of whom 161 (71%) suffered proximal MeVO and 66 (29%) distal MeVO. Using a combined approach in 96% of cases, successful reperfusion of the target vessel (mTICI 2b/2c/3) was attained in 85% of proximal MeVO and 97% of DMVO, with a median of 2 passes (IQR: 1-3) overall. Periprocedural complications rate was 7%. Control CT at day 1 post-MT revealed a hemorrhagic transformation in 63 (39%) patients with proximal MeVO and 24 (36%) patients with DMVO, with ECASS-PH type hemorrhagic transformations occurring in 3 (1%) patients. After 3 months, 58% of all MeVO and 63% of DMVO patients demonstrated a favorable outcome (mRS 0-2).

CONCLUSION: Mechanical thrombectomy using the pRESET LITE in a combined approach with an aspiration catheter appears effective for primary medium vessel occlusions across several centers and physicians.

Medienart:	E-Artikel

Erscheinungsjahr:	2024
Erschienen:	2024

Enthalten in:	Zur Gesamtaufnahme - volume:66
Enthalten in:	Neuroradiology - 66(2024), 4 vom: 21. März, Seite 631-641

Sprache:	Englisch

Beteiligte Personen:	Wang, Maud [VerfasserIn] Henkes, Hans [VerfasserIn] Ghozy, Sherief [VerfasserIn] Siegler, James E [VerfasserIn] Shaikh, Hamza [VerfasserIn] Khalife, Jane [VerfasserIn] Abdalkader, Mohamad [VerfasserIn] Klein, Piers [VerfasserIn] Nguyen, Thanh N [VerfasserIn] Heit, Jeremy J [VerfasserIn] Sweid, Ahmad [VerfasserIn] Naamani, Kareem El [VerfasserIn] Regenhardt, Robert W [VerfasserIn] Diestro, Jose Danilo Bengzon [VerfasserIn] Cancelliere, Nicole M [VerfasserIn] Amllay, Abdelaziz [VerfasserIn] Meyer, Lukas [VerfasserIn] Dusart, Anne [VerfasserIn] Bellante, Flavio [VerfasserIn] Forestier, Géraud [VerfasserIn] Rouchaud, Aymeric [VerfasserIn] Saleme, Suzana [VerfasserIn] Mounayer, Charbel [VerfasserIn] Fiehler, Jens [VerfasserIn] Kühn, Anna Luisa [VerfasserIn] Puri, Ajit S [VerfasserIn] Dyzmann, Christian [VerfasserIn] Kan, Peter T [VerfasserIn] Colasurdo, Marco [VerfasserIn] Marnat, Gaultier [VerfasserIn] Berge, Jérôme [VerfasserIn] Barreau, Xavier [VerfasserIn] Sibon, Igor [VerfasserIn] Nedelcu, Simona [VerfasserIn] Henninger, Nils [VerfasserIn] Weyland, Charlotte [VerfasserIn] Marotta, Thomas R [VerfasserIn] Stapleton, Christopher J [VerfasserIn] Rabinov, James D [VerfasserIn] Ota, Takahiro [VerfasserIn] Dofuku, Shogo [VerfasserIn] Yeo, Leonard Ll [VerfasserIn] Tan, Benjamin Y Q [VerfasserIn] Martinez-Gutierrez, Juan Carlos [VerfasserIn] Salazar-Marioni, Sergio [VerfasserIn] Sheth, Sunil [VerfasserIn] Renieri, Leonardo [VerfasserIn] Capirossi, Carolina [VerfasserIn] Mowla, Ashkan [VerfasserIn] Tjoumakaris, Stavropoula I [VerfasserIn] Jabbour, Pascal [VerfasserIn] Khandelwal, Priyank [VerfasserIn] Biswas, Arundhati [VerfasserIn] Clarençon, Frédéric [VerfasserIn] Elhorany, Mahmoud [VerfasserIn] Premat, Kevin [VerfasserIn] Valente, Iacopo [VerfasserIn] Pedicelli, Alessandro [VerfasserIn] Filipe, João Pedro [VerfasserIn] Varela, Ricardo [VerfasserIn] Quintero-Consuegra, Miguel [VerfasserIn] Gonzalez, Nestor R [VerfasserIn] Möhlenbruch, Markus A [VerfasserIn] Jesser, Jessica [VerfasserIn] Costalat, Vincent [VerfasserIn] Ter Schiphorst, Adrien [VerfasserIn] Yedavalli, Vivek [VerfasserIn] Harker, Pablo [VerfasserIn] Chervak, Lina M [VerfasserIn] Aziz, Yasmin [VerfasserIn] Gory, Benjamin [VerfasserIn] Stracke, Christian Paul [VerfasserIn] Hecker, Constantin [VerfasserIn] Killer-Oberpfalzer, Monika [VerfasserIn] Griessenauer, Christoph J [VerfasserIn] Thomas, Ajith J [VerfasserIn] Hsieh, Cheng-Yang [VerfasserIn] Liebeskind, David S [VerfasserIn] Radu, Răzvan Alexandru [VerfasserIn] Alexandre, Andrea M [VerfasserIn] Tancredi, Illario [VerfasserIn] Faizy, Tobias D [VerfasserIn] Patel, Aman B [VerfasserIn] Pereira, Vitor Mendes [VerfasserIn] Fahed, Robert [VerfasserIn] Lubicz, Boris [VerfasserIn] Dmytriw, Adam A [VerfasserIn] Guenego, Adrien [VerfasserIn] M.A.D.-M.T. Consortium [VerfasserIn]

Links:	Volltext

Themen:	Distal thrombectomy Endovascular recanalization Journal Article Medium vessel occlusion Review Stent retriever Stroke

Anmerkungen:	Date Completed 14.03.2024 Date Revised 29.03.2024 published: Print-Electronic Citation Status MEDLINE

doi:	10.1007/s00234-024-03302-5

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	NLM368711757

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Use of the pRESET LITE thrombectomy device in combined approach for medium vessel occlusions : A multicenter evaluation

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