Molecular complexity of intraductal carcinoma of the prostate

© 2024 The Authors. Cancer Medicine published by John Wiley & Sons Ltd..

Intraductal carcinoma of the prostate (IDC-P) is an aggressive subtype of prostate cancer characterized by the growth of tumor cells within the prostate ducts. It is often found alongside invasive carcinoma and is associated with poor prognosis. Understanding the molecular mechanisms driving IDC-P is crucial for improved diagnosis, prognosis, and treatment strategies. This review summarizes the molecular characteristics of IDC-P and their prognostic indications, comparing them to conventional prostate acinar adenocarcinoma, to gain insights into its unique behavior and identify potential therapeutic targets.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:13

Enthalten in:

Cancer medicine - 13(2024), 2 vom: 19. Jan., Seite e6939

Sprache:

Englisch

Beteiligte Personen:

Zhu, Sha [VerfasserIn]
Xu, Nanwei [VerfasserIn]
Zeng, Hao [VerfasserIn]

Links:

Volltext

Themen:

DNA damage and repair
Intraductal carcinoma of the prostate
Journal Article
MED12
MYC
Molecular characteristics
NCOR2
PTEN
Prostate acinar adenocarcinoma
RB1
Review
SChLAP1
TMPRSS2-ERG fusion
TP53
Targeted therapy

Anmerkungen:

Date Completed 22.02.2024

Date Revised 24.02.2024

published: Print

Citation Status MEDLINE

doi:

10.1002/cam4.6939

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM368693511