Assessment of myocardial strain patterns in patients with left bundle branch block using cardiac magnetic resonance
© 2024. The Author(s), under exclusive licence to Springer Nature B.V..
Recently, a classification with four types of septal longitudinal strain patterns was described using echocardiography, suggesting a pathophysiological continuum of left bundle branch block (LBBB)-induced left ventricle (LV) remodeling. The aim of this study was to assess the feasibility of classifying these strain patterns using cardiovascular magnetic resonance (CMR), and to evaluate their association with LV remodeling and myocardial scar. Single center registry included LBBB patients with septal flash (SF) referred to CMR to assess the cause of LV systolic dysfunction. Semi-automated feature-tracking cardiac resonance (FT-CMR) was used to quantify myocardial strain and detect the four strain patterns. A total of 115 patients were studied (age 66 ± 11 years, 57% men, 28% with ischemic heart disease). In longitudinal strain analysis, 23 patients (20%) were classified in stage LBBB-1, 37 (32.1%) in LBBB-2, 25 (21.7%) in LBBB-3, and 30 (26%) in LBBB-4. Patients at higher stages had more prominent septal flash, higher LV volumes, lower LV ejection fraction, and lower absolute strain values (p < 0.05 for all). Late gadolinium enhancement (LGE) was found in 55% of the patients (n = 63). No differences were found between the strain patterns regarding the presence, distribution or location of LGE. Among patients with LBBB, there was a good association between strain patterns assessed by FT-CMR analysis and the degree of LV remodeling and LV dysfunction. This association seems to be independent from the presence and distribution of LGE.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:40 |
|---|---|
| Enthalten in: |
The international journal of cardiovascular imaging - 40(2024), 4 vom: 25. Apr., Seite 801-809 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Santos, Marina Raquel [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
FT-CMR |
|---|
| Anmerkungen: |
Date Completed 26.04.2024 Date Revised 26.04.2024 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1007/s10554-024-03049-3 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM368667715 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM368667715 | ||
| 003 | DE-627 | ||
| 005 | 20240426233729.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240220s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s10554-024-03049-3 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1388.xml |
| 035 | |a (DE-627)NLM368667715 | ||
| 035 | |a (NLM)38376720 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Santos, Marina Raquel |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Assessment of myocardial strain patterns in patients with left bundle branch block using cardiac magnetic resonance |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 26.04.2024 | ||
| 500 | |a Date Revised 26.04.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2024. The Author(s), under exclusive licence to Springer Nature B.V. | ||
| 520 | |a Recently, a classification with four types of septal longitudinal strain patterns was described using echocardiography, suggesting a pathophysiological continuum of left bundle branch block (LBBB)-induced left ventricle (LV) remodeling. The aim of this study was to assess the feasibility of classifying these strain patterns using cardiovascular magnetic resonance (CMR), and to evaluate their association with LV remodeling and myocardial scar. Single center registry included LBBB patients with septal flash (SF) referred to CMR to assess the cause of LV systolic dysfunction. Semi-automated feature-tracking cardiac resonance (FT-CMR) was used to quantify myocardial strain and detect the four strain patterns. A total of 115 patients were studied (age 66 ± 11 years, 57% men, 28% with ischemic heart disease). In longitudinal strain analysis, 23 patients (20%) were classified in stage LBBB-1, 37 (32.1%) in LBBB-2, 25 (21.7%) in LBBB-3, and 30 (26%) in LBBB-4. Patients at higher stages had more prominent septal flash, higher LV volumes, lower LV ejection fraction, and lower absolute strain values (p < 0.05 for all). Late gadolinium enhancement (LGE) was found in 55% of the patients (n = 63). No differences were found between the strain patterns regarding the presence, distribution or location of LGE. Among patients with LBBB, there was a good association between strain patterns assessed by FT-CMR analysis and the degree of LV remodeling and LV dysfunction. This association seems to be independent from the presence and distribution of LGE | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a FT-CMR | |
| 650 | 4 | |a LBBB | |
| 650 | 4 | |a LV remodeling | |
| 650 | 4 | |a Septal flash | |
| 650 | 4 | |a Strain patterns | |
| 700 | 1 | |a Silva, Mariana Santos |e verfasserin |4 aut | |
| 700 | 1 | |a Guerreiro, Sara Lopes |e verfasserin |4 aut | |
| 700 | 1 | |a Gomes, Daniel Alberto |e verfasserin |4 aut | |
| 700 | 1 | |a Rocha, Bruno Miguel |e verfasserin |4 aut | |
| 700 | 1 | |a Cunha, Gonçalo Lopes |e verfasserin |4 aut | |
| 700 | 1 | |a Freitas, Pedro Nuno |e verfasserin |4 aut | |
| 700 | 1 | |a Abecasis, João Maria |e verfasserin |4 aut | |
| 700 | 1 | |a Santos, Ana Coutinho |e verfasserin |4 aut | |
| 700 | 1 | |a Saraiva, Carla Cristina |e verfasserin |4 aut | |
| 700 | 1 | |a Mendes, Miguel |e verfasserin |4 aut | |
| 700 | 1 | |a Ferreira, António Miguel |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t The international journal of cardiovascular imaging |d 2001 |g 40(2024), 4 vom: 25. Apr., Seite 801-809 |w (DE-627)NLM113949219 |x 1875-8312 |7 nnns |
| 773 | 1 | 8 | |g volume:40 |g year:2024 |g number:4 |g day:25 |g month:04 |g pages:801-809 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s10554-024-03049-3 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 40 |j 2024 |e 4 |b 25 |c 04 |h 801-809 | ||