Effects of hallucinogenic drugs on the human heart
Copyright © 2024 Neumann, Dhein, Kirchhefer, Hofmann and Gergs..
Hallucinogenic drugs are used because they have effects on the central nervous system. Their hallucinogenic effects probably occur via stimulation of serotonin receptors, namely, 5-HT2A-serotonin receptors in the brain. However, a close study reveals that they also act on the heart, possibly increasing the force of contraction and beating rate and may lead to arrhythmias. Here, we will review the inotropic and chronotropic actions of bufotenin, psilocin, psilocybin, lysergic acid diethylamide (LSD), ergotamine, ergometrine, N,N-dimethyltryptamine, and 5-methoxy-N,N-dimethyltryptamine in the human heart.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:15 |
|---|---|
| Enthalten in: |
Frontiers in pharmacology - 15(2024) vom: 14., Seite 1334218 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Neumann, Joachim [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Bufotenin |
|---|
| Anmerkungen: |
Date Revised 20.02.2024 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.3389/fphar.2024.1334218 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM36860537X |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM36860537X | ||
| 003 | DE-627 | ||
| 005 | 20240220232326.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240219s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3389/fphar.2024.1334218 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1300.xml |
| 035 | |a (DE-627)NLM36860537X | ||
| 035 | |a (NLM)38370480 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Neumann, Joachim |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Effects of hallucinogenic drugs on the human heart |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 20.02.2024 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Copyright © 2024 Neumann, Dhein, Kirchhefer, Hofmann and Gergs. | ||
| 520 | |a Hallucinogenic drugs are used because they have effects on the central nervous system. Their hallucinogenic effects probably occur via stimulation of serotonin receptors, namely, 5-HT2A-serotonin receptors in the brain. However, a close study reveals that they also act on the heart, possibly increasing the force of contraction and beating rate and may lead to arrhythmias. Here, we will review the inotropic and chronotropic actions of bufotenin, psilocin, psilocybin, lysergic acid diethylamide (LSD), ergotamine, ergometrine, N,N-dimethyltryptamine, and 5-methoxy-N,N-dimethyltryptamine in the human heart | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a LSD | |
| 650 | 4 | |a N,N-dimethyltryptamine | |
| 650 | 4 | |a bufotenin | |
| 650 | 4 | |a ergometrine | |
| 650 | 4 | |a ergotamine | |
| 650 | 4 | |a psilocin | |
| 650 | 4 | |a psilocybin | |
| 700 | 1 | |a Dhein, Stefan |e verfasserin |4 aut | |
| 700 | 1 | |a Kirchhefer, Uwe |e verfasserin |4 aut | |
| 700 | 1 | |a Hofmann, Britt |e verfasserin |4 aut | |
| 700 | 1 | |a Gergs, Ulrich |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Frontiers in pharmacology |d 2010 |g 15(2024) vom: 14., Seite 1334218 |w (DE-627)NLM208568891 |x 1663-9812 |7 nnns |
| 773 | 1 | 8 | |g volume:15 |g year:2024 |g day:14 |g pages:1334218 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.3389/fphar.2024.1334218 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 15 |j 2024 |b 14 |h 1334218 | ||