A promising pipeline of preclinical drug candidates for leishmaniasis and chronic Chagas' disease
Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved..
The drug discovery pipeline for leishmaniasis and trypanosomiasis has been filling with novel chemical entities with known mechanisms of action. González et al. and Braillard et al. report a cytochrome bc1 complex inhibitor as another promising preclinical candidate for visceral leishmaniasis (VL) and, in combination with benznidazole, for chronic Chagas' disease (CCD).
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:40 |
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| Enthalten in: |
Trends in parasitology - 40(2024), 3 vom: 10. März, Seite 211-213 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Saldivia, Manuel [VerfasserIn] |
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| Links: |
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| Themen: |
Chronic Chagas’ disease |
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| Anmerkungen: |
Date Completed 11.03.2024 Date Revised 26.03.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.pt.2024.02.002 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a The drug discovery pipeline for leishmaniasis and trypanosomiasis has been filling with novel chemical entities with known mechanisms of action. González et al. and Braillard et al. report a cytochrome bc1 complex inhibitor as another promising preclinical candidate for visceral leishmaniasis (VL) and, in combination with benznidazole, for chronic Chagas' disease (CCD) | ||
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