A custom-built step exergame training programme to prevent falls in people with multiple sclerosis : A multicentre randomised controlled trial
BACKGROUND: Cognitive-motor step training can improve stepping, balance and mobility in people with multiple sclerosis (MS), but effectiveness in preventing falls has not been demonstrated.
OBJECTIVES: This multisite randomised controlled trial aimed to determine whether 6 months of home-based step exergame training could reduce falls and improve associated risk factors compared with usual care in people with MS.
METHODS: In total, 461 people with MS aged 22-81 years were randomly allocated to usual care (control) or unsupervised home-based step exergame training (120 minutes/week) for 6 months. The primary outcome was rate of falls over 6 months from randomisation. Secondary outcomes included physical, cognitive and psychosocial function at 6 months and falls over 12 months.
RESULTS: Mean (standard deviation (SD)) weekly training duration was 70 (51) minutes over 6 months. Fall rates did not differ between intervention and control groups (incidence rates (95% confidence interval (CI)): 2.13 (1.57-2.69) versus 2.24 (1.35-3.13), respectively, incidence rate ratio: 0.96 (95% CI: 0.69-1.34, p = 0.816)). Intervention participants performed faster in tests of choice-stepping reaction time at 6 months. No serious training-related adverse events were reported.
CONCLUSION: The step exergame training programme did not reduce falls among people with MS. However, it significantly improved choice-stepping reaction time which is critical to ambulate safely in daily life environment.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:30 |
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| Enthalten in: |
Multiple sclerosis (Houndmills, Basingstoke, England) - 30(2024), 4-5 vom: 15. Apr., Seite 571-584 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Hoang, Phu [VerfasserIn] |
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| Links: |
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| Themen: |
Accidental falls |
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| Anmerkungen: |
Date Completed 12.04.2024 Date Revised 12.04.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1177/13524585241229360 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM36852938X |
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| 245 | 1 | 2 | |a A custom-built step exergame training programme to prevent falls in people with multiple sclerosis |b A multicentre randomised controlled trial |
| 264 | 1 | |c 2024 | |
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| 500 | |a Date Revised 12.04.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Cognitive-motor step training can improve stepping, balance and mobility in people with multiple sclerosis (MS), but effectiveness in preventing falls has not been demonstrated | ||
| 520 | |a OBJECTIVES: This multisite randomised controlled trial aimed to determine whether 6 months of home-based step exergame training could reduce falls and improve associated risk factors compared with usual care in people with MS | ||
| 520 | |a METHODS: In total, 461 people with MS aged 22-81 years were randomly allocated to usual care (control) or unsupervised home-based step exergame training (120 minutes/week) for 6 months. The primary outcome was rate of falls over 6 months from randomisation. Secondary outcomes included physical, cognitive and psychosocial function at 6 months and falls over 12 months | ||
| 520 | |a RESULTS: Mean (standard deviation (SD)) weekly training duration was 70 (51) minutes over 6 months. Fall rates did not differ between intervention and control groups (incidence rates (95% confidence interval (CI)): 2.13 (1.57-2.69) versus 2.24 (1.35-3.13), respectively, incidence rate ratio: 0.96 (95% CI: 0.69-1.34, p = 0.816)). Intervention participants performed faster in tests of choice-stepping reaction time at 6 months. No serious training-related adverse events were reported | ||
| 520 | |a CONCLUSION: The step exergame training programme did not reduce falls among people with MS. However, it significantly improved choice-stepping reaction time which is critical to ambulate safely in daily life environment | ||
| 650 | 4 | |a Randomized Controlled Trial | |
| 650 | 4 | |a Multicenter Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Accidental falls | |
| 650 | 4 | |a balance training | |
| 650 | 4 | |a cognitive training | |
| 650 | 4 | |a fall prevention | |
| 650 | 4 | |a multiple sclerosis | |
| 650 | 4 | |a randomised controlled trial | |
| 650 | 4 | |a stepping | |
| 700 | 1 | |a Sturnieks, Daina L |e verfasserin |4 aut | |
| 700 | 1 | |a Butler, Anna |e verfasserin |4 aut | |
| 700 | 1 | |a Chaplin, Carly |e verfasserin |4 aut | |
| 700 | 1 | |a Hicks, Cameron |e verfasserin |4 aut | |
| 700 | 1 | |a Lo, Joanne |e verfasserin |4 aut | |
| 700 | 1 | |a Ratanapongleka, Mayna |e verfasserin |4 aut | |
| 700 | 1 | |a Robinson, Sophie |e verfasserin |4 aut | |
| 700 | 1 | |a Smith, Natassia |e verfasserin |4 aut | |
| 700 | 1 | |a Turner, Jessica |e verfasserin |4 aut | |
| 700 | 1 | |a Krishnan, Arun V |e verfasserin |4 aut | |
| 700 | 1 | |a Barnett, Michael |e verfasserin |4 aut | |
| 700 | 1 | |a Gandevia, Simon |e verfasserin |4 aut | |
| 700 | 1 | |a Lord, Stephen R |e verfasserin |4 aut | |
| 700 | 1 | |a Menant, Jasmine C |e verfasserin |4 aut | |
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