Door-to-diuretic time and mortality in patients with acute heart failure : A systematic review and meta-analysis
Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved..
Early decongestion therapy with intravenous diuretics may be associated with improved outcomes in acute heart failure (AHF), however data is conflicting. This meta-analysis sought to evaluate the impact of door-to-IV diuretic (D2D) time on mortality in patients with AHF. Pooled estimates from observational studies comprising 28,124 patients, early IV diuresis (reference time 30-105 minutes) was associated with a 23% reduction in 30-day mortality in AHF (OR 0.77; 95% CI 0.64-0.93), despite no significant in-hospital death reduction (OR 0.84; 95% CI 0.57-1.24).
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2024 |
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Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - volume:269 |
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Enthalten in: |
American heart journal - 269(2024) vom: 15. Feb., Seite 205-209 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Sampaio Rodrigues, Thalys [VerfasserIn] |
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Anmerkungen: |
Date Completed 19.02.2024 Date Revised 19.02.2024 published: Print Citation Status MEDLINE |
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doi: |
10.1016/j.ahj.2023.12.012 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM368500772 |
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520 | |a Early decongestion therapy with intravenous diuretics may be associated with improved outcomes in acute heart failure (AHF), however data is conflicting. This meta-analysis sought to evaluate the impact of door-to-IV diuretic (D2D) time on mortality in patients with AHF. Pooled estimates from observational studies comprising 28,124 patients, early IV diuresis (reference time 30-105 minutes) was associated with a 23% reduction in 30-day mortality in AHF (OR 0.77; 95% CI 0.64-0.93), despite no significant in-hospital death reduction (OR 0.84; 95% CI 0.57-1.24) | ||
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