Effects of mint, menthol, and tobacco-flavored e-cigarettes on tobacco withdrawal symptoms in adults who smoke menthol cigarettes : A laboratory pilot study
Copyright © 2024 Elsevier B.V. All rights reserved..
BACKGROUND: Menthol cigarette smoking has remained stable or increased in certain groups, despite an overall decline in cigarette smoking rates in the U.S. Understanding whether e-cigarettes alter patterns of menthol cigarette use is critical to informing efforts for reducing the public health burden of menthol cigarette smoking. This 2019-2020 laboratory pilot study evaluated whether self-administration of mint-, menthol-, or tobacco-flavored e-cigarettes would differentially impact tobacco withdrawal symptoms in e-cigarette-naïve adults who smoke menthol cigarettes daily.
METHODS: Participants (N=17; 35.3% Female; mean age=51.8) attended three laboratory sessions after 16-hours of tobacco abstinence. Participants self-administered a study-provided JUUL e-cigarette (0.7mL with 5% nicotine by weight) at each session in which flavor was manipulated (mint vs. menthol vs. tobacco; order randomized). Participants completed pre- and post-e-cigarette administration self-report assessments on smoking urges, nicotine withdrawal, and positive and negative affect states. Multilevel linear regression models tested differences between the three flavor conditions for individual study outcomes.
RESULTS: Following overnight tobacco abstinence, vaping either a mint or menthol (vs. tobacco) flavored e-cigarette led to significantly greater reductions in smoking urges over time; menthol (vs. tobacco) flavored e-cigarettes also suppressed urges to smoke for pleasure. Notably, no differences in nicotine withdrawal, positive affect, or negative affect were observed.
CONCLUSIONS: In this laboratory pilot study, mint and menthol (vs. tobacco) flavored e-cigarettes provided some negative reinforcement effects via acute reductions in smoking urges during tobacco abstinence, yet only menthol flavored e-cigarettes demonstrated suppressive effects on smoking urges for pleasure in adults who smoke menthol cigarettes daily.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:256 |
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| Enthalten in: |
Drug and alcohol dependence - 256(2024) vom: 01. März, Seite 111110 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bello, Mariel S [VerfasserIn] |
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| Links: |
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| Themen: |
1490-04-6 |
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| Anmerkungen: |
Date Completed 04.03.2024 Date Revised 02.04.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.drugalcdep.2024.111110 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM36849697X |
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| 100 | 1 | |a Bello, Mariel S |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Effects of mint, menthol, and tobacco-flavored e-cigarettes on tobacco withdrawal symptoms in adults who smoke menthol cigarettes |b A laboratory pilot study |
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| 520 | |a Copyright © 2024 Elsevier B.V. All rights reserved. | ||
| 520 | |a BACKGROUND: Menthol cigarette smoking has remained stable or increased in certain groups, despite an overall decline in cigarette smoking rates in the U.S. Understanding whether e-cigarettes alter patterns of menthol cigarette use is critical to informing efforts for reducing the public health burden of menthol cigarette smoking. This 2019-2020 laboratory pilot study evaluated whether self-administration of mint-, menthol-, or tobacco-flavored e-cigarettes would differentially impact tobacco withdrawal symptoms in e-cigarette-naïve adults who smoke menthol cigarettes daily | ||
| 520 | |a METHODS: Participants (N=17; 35.3% Female; mean age=51.8) attended three laboratory sessions after 16-hours of tobacco abstinence. Participants self-administered a study-provided JUUL e-cigarette (0.7mL with 5% nicotine by weight) at each session in which flavor was manipulated (mint vs. menthol vs. tobacco; order randomized). Participants completed pre- and post-e-cigarette administration self-report assessments on smoking urges, nicotine withdrawal, and positive and negative affect states. Multilevel linear regression models tested differences between the three flavor conditions for individual study outcomes | ||
| 520 | |a RESULTS: Following overnight tobacco abstinence, vaping either a mint or menthol (vs. tobacco) flavored e-cigarette led to significantly greater reductions in smoking urges over time; menthol (vs. tobacco) flavored e-cigarettes also suppressed urges to smoke for pleasure. Notably, no differences in nicotine withdrawal, positive affect, or negative affect were observed | ||
| 520 | |a CONCLUSIONS: In this laboratory pilot study, mint and menthol (vs. tobacco) flavored e-cigarettes provided some negative reinforcement effects via acute reductions in smoking urges during tobacco abstinence, yet only menthol flavored e-cigarettes demonstrated suppressive effects on smoking urges for pleasure in adults who smoke menthol cigarettes daily | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Cigarette smoking | |
| 650 | 4 | |a E-cigarettes | |
| 650 | 4 | |a Menthol | |
| 650 | 4 | |a Mint flavor | |
| 650 | 4 | |a Smoking urges | |
| 650 | 4 | |a Tobacco abstinence | |
| 650 | 4 | |a Tobacco withdrawal | |
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| 700 | 1 | |a Ring, Colin R |e verfasserin |4 aut | |
| 700 | 1 | |a Cho, Junhan |e verfasserin |4 aut | |
| 700 | 1 | |a Barrington-Trimis, Jessica L |e verfasserin |4 aut | |
| 700 | 1 | |a Pang, Raina D |e verfasserin |4 aut | |
| 700 | 1 | |a Jao, Nancy C |e verfasserin |4 aut | |
| 700 | 1 | |a Colby, Suzanne M |e verfasserin |4 aut | |
| 700 | 1 | |a Cassidy, Rachel N |e verfasserin |4 aut | |
| 700 | 1 | |a Leventhal, Adam M |e verfasserin |4 aut | |
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