A new ratiometric fluorescent probe for rapid and highly selective detection of Cysteine in bovine serum
© 2024. The Author(s), under exclusive licence to The Japan Society for Analytical Chemistry..
As one of the most fundamental thiol compounds in the human body, cysteine (Cys) is involved in maintaining redox balance. Abnormal Cys levels can lead to various diseases. In this work, we successfully synthesized a fluorescent probe (CTBA) that can specifically detect Cys using acrylate as the reaction site, and CTBA has met the selectivity and anti-interference for Cys detection under optimized conditions. The linear range for Cys detection is between 0.05 and 100 μM and the detection limit is 0.0381 μM. Finally, this probe is used to detect the Cys content in three bovine serum samples and the test results are satisfactory.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:40 |
|---|---|
| Enthalten in: |
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry - 40(2024), 4 vom: 15. März, Seite 765-772 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Li, Changjian [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Acrylate |
|---|
| Anmerkungen: |
Date Completed 26.03.2024 Date Revised 26.03.2024 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1007/s44211-024-00516-8 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM368486818 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM368486818 | ||
| 003 | DE-627 | ||
| 005 | 20240326235425.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240215s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s44211-024-00516-8 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1348.xml |
| 035 | |a (DE-627)NLM368486818 | ||
| 035 | |a (NLM)38358582 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Li, Changjian |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A new ratiometric fluorescent probe for rapid and highly selective detection of Cysteine in bovine serum |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 26.03.2024 | ||
| 500 | |a Date Revised 26.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2024. The Author(s), under exclusive licence to The Japan Society for Analytical Chemistry. | ||
| 520 | |a As one of the most fundamental thiol compounds in the human body, cysteine (Cys) is involved in maintaining redox balance. Abnormal Cys levels can lead to various diseases. In this work, we successfully synthesized a fluorescent probe (CTBA) that can specifically detect Cys using acrylate as the reaction site, and CTBA has met the selectivity and anti-interference for Cys detection under optimized conditions. The linear range for Cys detection is between 0.05 and 100 μM and the detection limit is 0.0381 μM. Finally, this probe is used to detect the Cys content in three bovine serum samples and the test results are satisfactory | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Acrylate | |
| 650 | 4 | |a Bovine serum | |
| 650 | 4 | |a Cysteine | |
| 650 | 4 | |a Ratiometric fluorescent probe | |
| 650 | 7 | |a Fluorescent Dyes |2 NLM | |
| 650 | 7 | |a Cysteine |2 NLM | |
| 650 | 7 | |a K848JZ4886 |2 NLM | |
| 700 | 1 | |a Ji, Peng |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Xin |e verfasserin |4 aut | |
| 700 | 1 | |a Feng, Guodong |e verfasserin |4 aut | |
| 700 | 1 | |a Song, Zhiguang |e verfasserin |4 aut | |
| 700 | 1 | |a Guo, Yupeng |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Analytical sciences : the international journal of the Japan Society for Analytical Chemistry |d 1993 |g 40(2024), 4 vom: 15. März, Seite 765-772 |w (DE-627)NLM084854952 |x 1348-2246 |7 nnns |
| 773 | 1 | 8 | |g volume:40 |g year:2024 |g number:4 |g day:15 |g month:03 |g pages:765-772 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s44211-024-00516-8 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 40 |j 2024 |e 4 |b 15 |c 03 |h 765-772 | ||