Failure of bamlanivimab with selection of E484K mutation in an allogeneic stem cell transplant recipient with nosocomial SARS-CoV-2 infection
We report the case of an allogeneic stem cell transplant recipient with nosocomial acquisition of SARS-CoV-2 infection who received antispike neutralizing monoclonal antibody bamlanivimab 2 days after diagnosis of SARS-CoV-2 infection but progressed to severe COVID-19 pneumonia and died with the selection of E484K/Q resistance mutations to bamlanivimab.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:29 |
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| Enthalten in: |
Antiviral therapy - 29(2024), 1 vom: 22. Feb., Seite 13596535221097495 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Boussen, Inès [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 15.02.2024 Date Revised 22.02.2024 published: Print Citation Status MEDLINE |
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| doi: |
10.1177/13596535221097495 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM368435237 |
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| 520 | |a We report the case of an allogeneic stem cell transplant recipient with nosocomial acquisition of SARS-CoV-2 infection who received antispike neutralizing monoclonal antibody bamlanivimab 2 days after diagnosis of SARS-CoV-2 infection but progressed to severe COVID-19 pneumonia and died with the selection of E484K/Q resistance mutations to bamlanivimab | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a allogeneic stem cell transplant recipient | |
| 650 | 4 | |a bamlanivimab | |
| 650 | 4 | |a immune escape | |
| 650 | 4 | |a mutation | |
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| 700 | 1 | |a De Castro, Nathalie |e verfasserin |4 aut | |
| 700 | 1 | |a Delaugerre, Constance |e verfasserin |4 aut | |
| 700 | 1 | |a Chaix, Marie-Laure |e verfasserin |4 aut | |
| 700 | 1 | |a Molina, Jean-Michel |e verfasserin |4 aut | |
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