Pentacyclic triterpenes from the leaves of Camellia hakodae Ninh
Nine pentacyclic triterpene derivatives including new 3-O-cis-p-coumaroyl trichadenic acid B (1) and two new ursane-type triterpene derivatives, 11α,12-[1-(methyl)-2-(4-hydroxy-3-methoxyphenyl)ethane-1,2-dioxy]-urs-12-ene-3β-ol (2) and 11α,12-[2-(methyl)-1-(4-hydroxy-3-methoxyphenyl)ethane-1,2-dioxy]-urs-12-ene-3β-ol (3) were isolated from the leaves of Camellia hakodae Ninh., along with six known compounds (4-9). This is the first report on pentacyclic triterpenoids from this species. New compounds 1-3 and compound 7 were tested for cytotoxic activity against four human cancer cell lines (KB; Hep-G2; Lu; MCF-7) using the MTT assay to show moderate activity.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Natural product research - (2024) vom: 14. Feb., Seite 1-6 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Nguyen, Thanh Tuyen [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Revised 14.02.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1080/14786419.2024.2315597 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM368432661 |
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| 520 | |a Nine pentacyclic triterpene derivatives including new 3-O-cis-p-coumaroyl trichadenic acid B (1) and two new ursane-type triterpene derivatives, 11α,12-[1-(methyl)-2-(4-hydroxy-3-methoxyphenyl)ethane-1,2-dioxy]-urs-12-ene-3β-ol (2) and 11α,12-[2-(methyl)-1-(4-hydroxy-3-methoxyphenyl)ethane-1,2-dioxy]-urs-12-ene-3β-ol (3) were isolated from the leaves of Camellia hakodae Ninh., along with six known compounds (4-9). This is the first report on pentacyclic triterpenoids from this species. New compounds 1-3 and compound 7 were tested for cytotoxic activity against four human cancer cell lines (KB; Hep-G2; Lu; MCF-7) using the MTT assay to show moderate activity | ||
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| 650 | 4 | |a 11α,12-[1-(methyl)-2-(4-hydroxy-3-methoxyphenyl)ethane-1,2-dioxy]-urs-12-ene-3β-ol | |
| 650 | 4 | |a 11α,12-[2-(methyl)-1-(4-hydroxy-3-methoxyphenyl)ethane-1,2-dioxy]-urs-12-ene-3β-ol | |
| 650 | 4 | |a 3-O-cis-p-coumaroyl trichadenic acid B | |
| 650 | 4 | |a Camellia hakodae Ninh | |
| 650 | 4 | |a cytotoxic activity | |
| 650 | 4 | |a ursane-type triterpenes | |
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| 700 | 1 | |a Vu, Minh Tin |e verfasserin |4 aut | |
| 700 | 1 | |a Vu, Dinh Hoang |e verfasserin |4 aut | |
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