A nomogram for predicting risk factors of testicular salvage after testicular torsion in children
© 2024 The Authors. International Journal of Urology published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Urological Association..
OBJECTIVES: This study aimed to establish a nomogram for predicting the probability of testicular salvage after testicular torsion in children.
METHODS: We retrospectively collected data of children with testicular torsion who were treated at Shenzhen Children's Hospital between September 2005 and August 2022. Of the training cohort, 113 patients who underwent orchiectomy and five with testicular atrophy after orchiopexy were included in the failed testicular salvage group. Additionally, 37 patients who underwent orchiopexy without postoperative testicular atrophy were included in the successful testicular salvage group. The predictive factors affecting testicular salvage were determined using univariate and multivariate logistic regression analyses; a nomogram was constructed. The nomogram was verified using data from the validation group.
RESULTS: Using multivariate logistic regression analysis, the independent risk factors of testicular salvage after testicular torsion were symptom duration (p = 0.034), intratesticular blood flow (p = 0.003), spermatic cord torsion degree (p = 0.037), and monocyte count (odds ratio: 0.012, p = 0.036). A nomogram was established based on these four risk factors. In the training cohort, the area under the receiver operating characteristic curve was 0.969. The area under the receiver operating characteristic curve of the verification cohort was 0.965, indicating good discrimination ability of the nomogram. Increased symptom duration without intratesticular blood flow increased the monocyte count and spermatic cord torsion degree and decreased the success rate of testicular salvage.
CONCLUSION: This prediction model could obtain the corresponding probability of testicular salvage according to the clinical characteristics of different patients with testicular torsion, providing reference for clinicians and parents.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:31 |
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| Enthalten in: |
International journal of urology : official journal of the Japanese Urological Association - 31(2024), 5 vom: 04. Mai, Seite 568-574 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Chen, Pengyu [VerfasserIn] |
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| Links: |
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| Themen: |
Hemodynamics |
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| Anmerkungen: |
Date Completed 04.05.2024 Date Revised 04.05.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1111/iju.15420 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM368293661 |
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| 245 | 1 | 2 | |a A nomogram for predicting risk factors of testicular salvage after testicular torsion in children |
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| 500 | |a Date Revised 04.05.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2024 The Authors. International Journal of Urology published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Urological Association. | ||
| 520 | |a OBJECTIVES: This study aimed to establish a nomogram for predicting the probability of testicular salvage after testicular torsion in children | ||
| 520 | |a METHODS: We retrospectively collected data of children with testicular torsion who were treated at Shenzhen Children's Hospital between September 2005 and August 2022. Of the training cohort, 113 patients who underwent orchiectomy and five with testicular atrophy after orchiopexy were included in the failed testicular salvage group. Additionally, 37 patients who underwent orchiopexy without postoperative testicular atrophy were included in the successful testicular salvage group. The predictive factors affecting testicular salvage were determined using univariate and multivariate logistic regression analyses; a nomogram was constructed. The nomogram was verified using data from the validation group | ||
| 520 | |a RESULTS: Using multivariate logistic regression analysis, the independent risk factors of testicular salvage after testicular torsion were symptom duration (p = 0.034), intratesticular blood flow (p = 0.003), spermatic cord torsion degree (p = 0.037), and monocyte count (odds ratio: 0.012, p = 0.036). A nomogram was established based on these four risk factors. In the training cohort, the area under the receiver operating characteristic curve was 0.969. The area under the receiver operating characteristic curve of the verification cohort was 0.965, indicating good discrimination ability of the nomogram. Increased symptom duration without intratesticular blood flow increased the monocyte count and spermatic cord torsion degree and decreased the success rate of testicular salvage | ||
| 520 | |a CONCLUSION: This prediction model could obtain the corresponding probability of testicular salvage according to the clinical characteristics of different patients with testicular torsion, providing reference for clinicians and parents | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a hemodynamics | |
| 650 | 4 | |a monocytes | |
| 650 | 4 | |a orchiectomy | |
| 650 | 4 | |a orchiopexy | |
| 650 | 4 | |a testicular torsion | |
| 700 | 1 | |a Huang, Weipeng |e verfasserin |4 aut | |
| 700 | 1 | |a He, Yingying |e verfasserin |4 aut | |
| 700 | 1 | |a Sun, Mengkui |e verfasserin |4 aut | |
| 700 | 1 | |a Sun, Xuerui |e verfasserin |4 aut | |
| 700 | 1 | |a Huang, Yiyan |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Shoulin |e verfasserin |4 aut | |
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