Reporting of determinants of health inequities and participant characteristics in randomized controlled trials of systemic lupus erythematosus in Canada : A scoping review

OBJECTIVE: To report participant characteristics relevant to identifying health inequities in systemic lupus erythematosus (SLE) randomized controlled trials conducted in Canada.

METHODS: We conducted a scoping review by searching MEDLINE (Ovid) and Embase (1990 to June 2023), and CENTRAL (inception to June 2023). Eligible studies: used an RCT design; evaluated interventions (pharmacologic and non-pharmacologic) among SLE patients aged ≥18 years; and were conducted in Canada. Data extraction was guided by the Campbell and Cochrane Equity Methods Group's PROGRESS-Plus framework on 11 factors leading to health inequities (Place of residence; Race, culture, ethnicity, and language; Occupation; Gender and sex; Religion; Education; Socioeconomic status; Social capital; Plus: Personal characteristics associated with discrimination; Features of relationships; and Time-dependent relationships).

RESULTS: Of 1901 unique records, 6 met the inclusion criteria. Sex and age were the only PROGRESS factors that were reported in all studies. The majority of participants were female (84.4% to 100%), and mean ages of participants ranged from 42 to 52.3 years. Place of residence, race, education, and social capital were reported in three studies. Socioeconomic status was reported in two studies, and occupation was reported in one study. Religion, features of relationships, and time-dependent relationships were not reported in any included studies.

CONCLUSION: Limited reporting of determinants of health inequities in RCTs for SLE in Canada suggests the need for reporting standards to support equity, diversity, and inclusion practices in research.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:33

Enthalten in:

Lupus - 33(2024), 5 vom: 10. März, Seite 462-469

Sprache:

Englisch

Beteiligte Personen:

Thomas, Megan [VerfasserIn]
Verma, Vanay [VerfasserIn]
Gheshlaghi, Niloofar [VerfasserIn]
Esdaile, John [VerfasserIn]
Avina-Zubieta, Antonio [VerfasserIn]
Barnabe, Cheryl [VerfasserIn]
Harrison, Mark [VerfasserIn]
De Vera, Mary A [VerfasserIn]

Links:

Volltext

Themen:

Equity, diversity, and inclusion
Journal Article
Review
Scoping review
Systemic lupus erythematosus

Anmerkungen:

Date Completed 22.03.2024

Date Revised 23.03.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1177/09612033241233032

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM368292908