Ocular syphilis masquerading as refractory retinal diseases
© 2024. The Author(s)..
PURPOSE: To report two cases of syphilis masquerading as chronic refractory macular diseases.
CASE DESCRIPTIONS: Two patients had been diagnosed with neovascular age-related macular degeneration (neovascular AMD) and diabetic macular edema (DME), respectively. The disease worsened despite repeated intravitreal injections of anti-vascular endothelial growth factor (VEGF) and also surgical treatment (in suspected case of DME). Systemic evaluations were positive for syphilis. Intravenous penicillin was started, and the macular diseases improved. The lesions were well controlled afterward.
CONCLUSIONS: The current two cases demonstrated that ocular syphilis can masquerade as refractory chronic retinal diseases such as DME and neovascular AMD. Laboratory evaluations for syphilis may be needed, not only for uveitis but also for refractory retinal diseases. Indocyanine green angiography may be helpful to reveal occult syphilis.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:24 |
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| Enthalten in: |
BMC infectious diseases - 24(2024), 1 vom: 07. Feb., Seite 165 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Park, Sung Who [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 09.02.2024 Date Revised 10.02.2024 published: Electronic Citation Status MEDLINE |
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| doi: |
10.1186/s12879-023-08739-2 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM368160238 |
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| 520 | |a © 2024. The Author(s). | ||
| 520 | |a PURPOSE: To report two cases of syphilis masquerading as chronic refractory macular diseases | ||
| 520 | |a CASE DESCRIPTIONS: Two patients had been diagnosed with neovascular age-related macular degeneration (neovascular AMD) and diabetic macular edema (DME), respectively. The disease worsened despite repeated intravitreal injections of anti-vascular endothelial growth factor (VEGF) and also surgical treatment (in suspected case of DME). Systemic evaluations were positive for syphilis. Intravenous penicillin was started, and the macular diseases improved. The lesions were well controlled afterward | ||
| 520 | |a CONCLUSIONS: The current two cases demonstrated that ocular syphilis can masquerade as refractory chronic retinal diseases such as DME and neovascular AMD. Laboratory evaluations for syphilis may be needed, not only for uveitis but also for refractory retinal diseases. Indocyanine green angiography may be helpful to reveal occult syphilis | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Age related macular degeneration | |
| 650 | 4 | |a Choroidal neovascularization | |
| 650 | 4 | |a Diabetic macular edema | |
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| 700 | 1 | |a Byon, Ik Soo |e verfasserin |4 aut | |
| 700 | 1 | |a Khan, Youan Hasan |e verfasserin |4 aut | |
| 700 | 1 | |a Nguyen, Quan Dong |e verfasserin |4 aut | |
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