Single versus multiple arterial coronary artery bypass grafting in men and women : results from Polish National Registry of Cardiac Surgery Procedures
Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc..
BACKGROUND: The objective of this multicenter study aimed to investigate the impact of sex on long-term survival among patients with multivessel coronary artery disease undergoing coronary artery bypass grafting (CABG) using multiple arterial grafting (MAG) or a single artery with saphenous vein grafts.
MATERIALS AND METHODS: Data were obtained from the Polish National Registry of Cardiac Surgery Procedures database. This study included 81 136 patients who underwent CABG for multivessel disease between January 2012 and December 2020 (22.9 were women and 77.1% were men). MAG was performed in 8.3 and 11.7% of female and male patients, respectively. A 1:1 propensity score (PS)-matching was performed. Long-term mortality was compared between matched groups of men and women. Subgroup analyses of patients aged <70 and ≥70 years, with an ejection fraction (EF) >40% and ≤40%, and with and without diabetes, obesity, peripheral artery disease (PAD), or chronic lung disease (CLD) were performed separately in women and men.
RESULTS: MAG was associated with lower long-term mortality than saphenous vein grafts in 1528 PS-matched female pairs [hazard ratio (HR): 0.74; 95% CI: 0.59-0.92; P =0.007) and 7283 PS-matched male pairs (HR: 0.80; 95% CI: 0.72-0.88; P <0.001). Subgroup analyses confirmed the results among female patients aged <70 years, with diabetes and EF >40%, and without PAD or CLD, and of male patients aged <70 and ≥70 years; with EF >40%; with or without diabetes, obesity, or PAD; and without CLD.
CONCLUSIONS: In patients undergoing CABG, MAG was associated with significantly improved survival in both sexes. The long-term benefits of MAG observed across subgroups of men and women support the consideration of a multiarterial revascularization strategy for a broader spectrum of patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:110 |
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| Enthalten in: |
International journal of surgery (London, England) - 110(2024), 4 vom: 01. Apr., Seite 2234-2242 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Aboul-Hassan, Sleiman Sebastian [VerfasserIn] |
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| Anmerkungen: |
Date Completed 26.04.2024 Date Revised 26.04.2024 published: Electronic Citation Status MEDLINE |
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| doi: |
10.1097/JS9.0000000000001133 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM368134555 |
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| 100 | 1 | |a Aboul-Hassan, Sleiman Sebastian |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Single versus multiple arterial coronary artery bypass grafting in men and women |b results from Polish National Registry of Cardiac Surgery Procedures |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
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| 500 | |a Date Completed 26.04.2024 | ||
| 500 | |a Date Revised 26.04.2024 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. | ||
| 520 | |a BACKGROUND: The objective of this multicenter study aimed to investigate the impact of sex on long-term survival among patients with multivessel coronary artery disease undergoing coronary artery bypass grafting (CABG) using multiple arterial grafting (MAG) or a single artery with saphenous vein grafts | ||
| 520 | |a MATERIALS AND METHODS: Data were obtained from the Polish National Registry of Cardiac Surgery Procedures database. This study included 81 136 patients who underwent CABG for multivessel disease between January 2012 and December 2020 (22.9 were women and 77.1% were men). MAG was performed in 8.3 and 11.7% of female and male patients, respectively. A 1:1 propensity score (PS)-matching was performed. Long-term mortality was compared between matched groups of men and women. Subgroup analyses of patients aged <70 and ≥70 years, with an ejection fraction (EF) >40% and ≤40%, and with and without diabetes, obesity, peripheral artery disease (PAD), or chronic lung disease (CLD) were performed separately in women and men | ||
| 520 | |a RESULTS: MAG was associated with lower long-term mortality than saphenous vein grafts in 1528 PS-matched female pairs [hazard ratio (HR): 0.74; 95% CI: 0.59-0.92; P =0.007) and 7283 PS-matched male pairs (HR: 0.80; 95% CI: 0.72-0.88; P <0.001). Subgroup analyses confirmed the results among female patients aged <70 years, with diabetes and EF >40%, and without PAD or CLD, and of male patients aged <70 and ≥70 years; with EF >40%; with or without diabetes, obesity, or PAD; and without CLD | ||
| 520 | |a CONCLUSIONS: In patients undergoing CABG, MAG was associated with significantly improved survival in both sexes. The long-term benefits of MAG observed across subgroups of men and women support the consideration of a multiarterial revascularization strategy for a broader spectrum of patients | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 700 | 1 | |a Hirnle, Grzegorz |e verfasserin |4 aut | |
| 700 | 1 | |a Perek, Bartlomiej |e verfasserin |4 aut | |
| 700 | 1 | |a Jemielity, Marek |e verfasserin |4 aut | |
| 700 | 1 | |a Hirnle, Tomasz |e verfasserin |4 aut | |
| 700 | 1 | |a Brykczynski, Miroslaw |e verfasserin |4 aut | |
| 700 | 1 | |a Deja, Marek |e verfasserin |4 aut | |
| 700 | 1 | |a Rogowski, Jan |e verfasserin |4 aut | |
| 700 | 1 | |a Cisowski, Marek |e verfasserin |4 aut | |
| 700 | 1 | |a Krejca, Michal |e verfasserin |4 aut | |
| 700 | 1 | |a Anisimowicz, Lech |e verfasserin |4 aut | |
| 700 | 1 | |a Widenka, Kazimierz |e verfasserin |4 aut | |
| 700 | 1 | |a Gerber, Witold |e verfasserin |4 aut | |
| 700 | 1 | |a Pacholewicz, Jerzy |e verfasserin |4 aut | |
| 700 | 1 | |a Bugajski, Pawel |e verfasserin |4 aut | |
| 700 | 1 | |a Stepinski, Piotr |e verfasserin |4 aut | |
| 700 | 1 | |a Maruszewski, Bohdan J |e verfasserin |4 aut | |
| 700 | 1 | |a Cichon, Romuald |e verfasserin |4 aut | |
| 700 | 1 | |a Hrapkowicz, Tomasz |e verfasserin |4 aut | |
| 700 | 0 | |a KROK Investigators |e verfasserin |4 aut | |
| 700 | 1 | |a Kapelak, Boguslaw |e investigator |4 oth | |
| 700 | 1 | |a Kolsut, Piotr |e investigator |4 oth | |
| 700 | 1 | |a Suwalski, Piotr |e investigator |4 oth | |
| 700 | 1 | |a Jasinski, Marek |e investigator |4 oth | |
| 700 | 1 | |a Przybylski, Roman |e investigator |4 oth | |
| 700 | 1 | |a Skiba, Jacek |e investigator |4 oth | |
| 700 | 1 | |a Stanislawski, Ryszard |e investigator |4 oth | |
| 700 | 1 | |a Kwinecki, Pawel |e investigator |4 oth | |
| 700 | 1 | |a Tomczyk, Remigiusz |e investigator |4 oth | |
| 700 | 1 | |a Religa, Grzegorz |e investigator |4 oth | |
| 700 | 1 | |a Pietrzyk, Edward |e investigator |4 oth | |
| 700 | 1 | |a Gryszko, Leszek |e investigator |4 oth | |
| 700 | 1 | |a Wrobel, Krzysztof |e investigator |4 oth | |
| 700 | 1 | |a Tulecki, Lukasz |e investigator |4 oth | |
| 700 | 1 | |a Jarmoszewicz, Krzysztof |e investigator |4 oth | |
| 700 | 1 | |a Karpeta, Kamil |e investigator |4 oth | |
| 700 | 1 | |a Zelazny, Piotr |e investigator |4 oth | |
| 700 | 1 | |a Kusmierczyk, Mariusz |e investigator |4 oth | |
| 700 | 1 | |a Burysz, Marian |e investigator |4 oth | |
| 700 | 1 | |a Stazka, Janusz |e investigator |4 oth | |
| 700 | 1 | |a Zembala, Marian |e investigator |4 oth | |
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