Allergen-specific immunotherapy : A brief overview in association with allergic conjunctivitis

© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature..

Allergen-specific immunotherapy (AIT) is the only causal and disease-modifying treatment for immunoglobulin E (IgE)-mediated type I allergies. Regular exposure to the causative allergen results in an immunomodulatory effect by which the predominant T‑helper (Th) 2 lymphocyte response is shifted to a Th1 lymphocyte response and more allergen-specific blocking immunoglobulins are produced. The approval of substances for AIT is regulated by the Therapy Allergens Ordinance (TAV). There are subcutaneous and/or sublingual AITs for the following indications: allergic rhinitis, allergic conjunctivitis, allergic asthma and insect venom allergy. In this article the indications for allergic conjunctivitis are discussed in particular. Clinical symptoms and a relevant type 1 sensitization are the prerequisites for the indications for AIT. The assessment of the indications and carrying out an AIT should only be carried out by physicians who have been trained in allergology.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:121

Enthalten in:

Die Ophthalmologie - 121(2024), 3 vom: 26. März, Seite 187-195

Sprache:

Deutsch

Weiterer Titel:

Allergenspezifische Immuntherapie : Ein kurzer Überblick im Zusammenhang mit der allergischen Konjunktivitis

Beteiligte Personen:

Lill, Diana [VerfasserIn]
Bertlich, Mattis [VerfasserIn]
Oppel, Eva [VerfasserIn]

Links:

Volltext

Themen:

37341-29-0
Allergens
Allergic conjunctivitis
English Abstract
Immunoglobulin E
Immunoglobulins
Journal Article
Review
Subcutaneous immunotherapy
Sublingual Immunotherapy
Therapy Allergens Ordinance

Anmerkungen:

Date Completed 07.03.2024

Date Revised 04.04.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s00347-024-01987-w

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM368132250