Coagulation Testing in Real-World Setting : Insights From a Comprehensive Survey

The objective of this survey was to gain a real-world perspective on coagulation testing by evaluating the availability of various coagulation laboratory tests, assessing specific analytic and postanalytic steps in clinical laboratories in Korea.Participants were surveyed using a 65-question questionnaire specifically focused on their coagulation testing practices related to prothrombin time (PT), activated partial thromboplastin time (aPTT), plasma-mixing studies, lupus anticoagulant (LA) tests, platelet function tests, coagulation factor assays, and the composition of hemostasis and thrombosis test panels. The survey was performed between July and September 2022.The survey achieved a 77.9% (81 of 104) response rate. PT or aPTT tests were performed directly at all participating institutions, followed by D-dimer and fibrinogen tests, platelet function test, and plasma-mixing studies in order of frequency. Variations existed in the performance of mixing test and LA assessment. Patterns of coagulating testing differed depending on the size of the hospital. The survey revealed that most laboratories conducted coagulation tests following the international guidelines such as Clinical Laboratory Standards Institute guidelines and the Korean Laboratory Certification system. However, some coagulation tests, including mixing test and LA tests, are yet to be standardized in Korea.Continuous education on coagulation test methods and internal and external quality control are required to encourage laboratories to enhance the performance of coagulation testing.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:30

Enthalten in:

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 30(2024) vom: 06. Jan., Seite 10760296241228239

Sprache:

Englisch

Beteiligte Personen:

Bang, Hae In [VerfasserIn]
Lee, Ja Young [VerfasserIn]
Kim, Hyun-Young [VerfasserIn]
Shin, Saeam [VerfasserIn]
Nam, Myung Hyun [VerfasserIn]
Kim, In-Suk [VerfasserIn]
Kim, Ji Myung [VerfasserIn]
Yoon, Jong-Hyun [VerfasserIn]
Shin, Myung-Geun [VerfasserIn]
Hwang, Sang Mee [VerfasserIn]
Kong, Sun-Young [VerfasserIn]

Links:

Volltext

Themen:

Blood coagulation
Journal Article
Lupus Coagulation Inhibitor
Lupus anticoagulant
Plasma-mixing studies
Platelet function tests
Standardization
Surveys and questionnaires

Anmerkungen:

Date Completed 08.02.2024

Date Revised 10.02.2024

published: Print

Citation Status MEDLINE

doi:

10.1177/10760296241228239

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM368109844