Clinical and laboratory parameters and pathomorphological features of the lungs in patients who have had COVID-19 viral pneumonia

Post-Covid syndrome is characterized by general somatic manifestations, changes in the psycho-emotional sphere, cognitive disorders, disorders of the cardiovascular, respiratory systems and excretory function. However, there is little information in the literature about the mechanisms of thanatogenesis in patients who have had COVID-19. An analysis of clinical and laboratory parameters and pathomorphological changes was carried out in 9 autopsy cases of patients who had previously suffered a new coronavirus infection (COVID-19). The age of the deceased ranged from 80 to 96 years. At the time of hospitalization, the concentration of IgG varied from 32.61 to 1013.5 RLU, IgM - from 0.29 to 16.98 U/ml. The period from clinical diagnosis to death ranged from 12 to 46 days, and the time from clinical recovery (negative polymerase chain reaction) to death ranged from 2 to 30 days. In all cases, unresolved viral pneumonia and diffuse alveolar damage (exudative-proliferative phase) were diagnosed.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:86

Enthalten in:

Arkhiv patologii - 86(2024), 1 vom: 06., Seite 27-35

Sprache:

Russisch

Weiterer Titel:

Kliniko-laboratornye pokazateli i patomorfologicheskie osobennosti legkikh u patsientov, perenesshikh virusnuyu pnevmoniyu COVID-19

Beteiligte Personen:

Kontorshchikov, A S [VerfasserIn]
Mikhaleva, L M [VerfasserIn]
Sharafetdinova, M A [VerfasserIn]
Vasyukova, O A [VerfasserIn]
Kozlov, I S [VerfasserIn]
Vandysheva, R A [VerfasserIn]
Kakturskiy, L V [VerfasserIn]

Links:

Volltext

Themen:

Early convalescence phase
English Abstract
Ig G
IgM
Immunohistochemistry
Journal Article
Novel coronavirus infection (COVID-19)
Pathology
SARS-CoV-2

Anmerkungen:

Date Completed 07.02.2024

Date Revised 07.02.2024

published: Print

Citation Status MEDLINE

doi:

10.17116/patol20248601127

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM368085392