Prevalence, predictors, and patient-reported outcomes of long COVID in hospitalized and non-hospitalized patients from the city of São Paulo, Brazil
Copyright © 2024 Malheiro, Bernardez-Pereira, Parreira, Pagliuso, de Paula Gomes, de Mesquita Escobosa, de Araújo, Pimenta, Lin, de Almeida, Tuma, Laselva, Neto, Klajner, Teich, Kobayashi, Edmond and Marra..
Background: Robust data comparing long COVID in hospitalized and non-hospitalized patients in middle-income countries are limited.
Methods: A retrospective cohort study was conducted in Brazil, including hospitalized and non-hospitalized patients. Long COVID was diagnosed at 90-day follow-up using WHO criteria. Demographic and clinical information, including the depression screening scale (PHQ-2) at day 30, was compared between the groups. If the PHQ-2 score is 3 or greater, major depressive disorder is likely. Logistic regression analysis identified predictors and protective factors for long COVID.
Results: A total of 291 hospitalized and 1,118 non-hospitalized patients with COVID-19 were included. The prevalence of long COVID was 47.1% and 49.5%, respectively. Multivariable logistic regression showed female sex (odds ratio [OR] = 4.50, 95% confidence interval (CI) 2.51-8.37), hypertension (OR = 2.90, 95% CI 1.52-5.69), PHQ-2 > 3 (OR = 6.50, 95% CI 1.68-33.4) and corticosteroid use during hospital stay (OR = 2.43, 95% CI 1.20-5.04) as predictors of long COVID in hospitalized patients, while female sex (OR = 2.52, 95% CI 1.95-3.27) and PHQ-2 > 3 (OR = 3.88, 95% CI 2.52-6.16) were predictors in non-hospitalized patients.
Conclusion: Long COVID was prevalent in both groups. Positive depression screening at day 30 post-infection can predict long COVID. Early screening of depression helps health staff to identify patients at a higher risk of long COVID, allowing an early diagnosis of the condition.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
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| Enthalten in: |
Frontiers in public health - 11(2023) vom: 30., Seite 1302669 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Malheiro, Daniel Tavares [VerfasserIn] |
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| Links: |
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| Themen: |
Depression screening |
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| Anmerkungen: |
Date Completed 07.02.2024 Date Revised 07.02.2024 published: Electronic-eCollection Citation Status MEDLINE |
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| doi: |
10.3389/fpubh.2023.1302669 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM368069494 |
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| 100 | 1 | |a Malheiro, Daniel Tavares |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Prevalence, predictors, and patient-reported outcomes of long COVID in hospitalized and non-hospitalized patients from the city of São Paulo, Brazil |
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| 500 | |a Date Completed 07.02.2024 | ||
| 500 | |a Date Revised 07.02.2024 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2024 Malheiro, Bernardez-Pereira, Parreira, Pagliuso, de Paula Gomes, de Mesquita Escobosa, de Araújo, Pimenta, Lin, de Almeida, Tuma, Laselva, Neto, Klajner, Teich, Kobayashi, Edmond and Marra. | ||
| 520 | |a Background: Robust data comparing long COVID in hospitalized and non-hospitalized patients in middle-income countries are limited | ||
| 520 | |a Methods: A retrospective cohort study was conducted in Brazil, including hospitalized and non-hospitalized patients. Long COVID was diagnosed at 90-day follow-up using WHO criteria. Demographic and clinical information, including the depression screening scale (PHQ-2) at day 30, was compared between the groups. If the PHQ-2 score is 3 or greater, major depressive disorder is likely. Logistic regression analysis identified predictors and protective factors for long COVID | ||
| 520 | |a Results: A total of 291 hospitalized and 1,118 non-hospitalized patients with COVID-19 were included. The prevalence of long COVID was 47.1% and 49.5%, respectively. Multivariable logistic regression showed female sex (odds ratio [OR] = 4.50, 95% confidence interval (CI) 2.51-8.37), hypertension (OR = 2.90, 95% CI 1.52-5.69), PHQ-2 > 3 (OR = 6.50, 95% CI 1.68-33.4) and corticosteroid use during hospital stay (OR = 2.43, 95% CI 1.20-5.04) as predictors of long COVID in hospitalized patients, while female sex (OR = 2.52, 95% CI 1.95-3.27) and PHQ-2 > 3 (OR = 3.88, 95% CI 2.52-6.16) were predictors in non-hospitalized patients | ||
| 520 | |a Conclusion: Long COVID was prevalent in both groups. Positive depression screening at day 30 post-infection can predict long COVID. Early screening of depression helps health staff to identify patients at a higher risk of long COVID, allowing an early diagnosis of the condition | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a depression screening | |
| 650 | 4 | |a long COVID | |
| 650 | 4 | |a mental health | |
| 650 | 4 | |a middle income countries | |
| 650 | 4 | |a quality of life | |
| 700 | 1 | |a Bernardez-Pereira, Sabrina |e verfasserin |4 aut | |
| 700 | 1 | |a Parreira, Kauê Capellato Junqueira |e verfasserin |4 aut | |
| 700 | 1 | |a Pagliuso, João Gabriel Dias |e verfasserin |4 aut | |
| 700 | 1 | |a de Paula Gomes, Emerson |e verfasserin |4 aut | |
| 700 | 1 | |a de Mesquita Escobosa, Daisa |e verfasserin |4 aut | |
| 700 | 1 | |a de Araújo, Carolina Ivo |e verfasserin |4 aut | |
| 700 | 1 | |a Pimenta, Beatriz Silva |e verfasserin |4 aut | |
| 700 | 1 | |a Lin, Vivian |e verfasserin |4 aut | |
| 700 | 1 | |a de Almeida, Silvana Maria |e verfasserin |4 aut | |
| 700 | 1 | |a Tuma, Paula |e verfasserin |4 aut | |
| 700 | 1 | |a Laselva, Claudia Regina |e verfasserin |4 aut | |
| 700 | 1 | |a Neto, Miguel Cendoroglo |e verfasserin |4 aut | |
| 700 | 1 | |a Klajner, Sidney |e verfasserin |4 aut | |
| 700 | 1 | |a Teich, Vanessa Damazio |e verfasserin |4 aut | |
| 700 | 1 | |a Kobayashi, Takaaki |e verfasserin |4 aut | |
| 700 | 1 | |a Edmond, Michael B |e verfasserin |4 aut | |
| 700 | 1 | |a Marra, Alexandre R |e verfasserin |4 aut | |
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