Pylephlebitis-induced acute liver failure : A case report and review of literature
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved..
BACKGROUND: Pylephlebitis is an extremely rare form of septic thrombophlebitis involving the portal vein, carrying high rates of morbidity and mortality.
CASE SUMMARY: We present a case of a 42-year-old male with no past medical history who presented with acute onset of abdominal pain and altered mental status with laboratory tests demonstrating new-onset acute liver failure. Pylephlebitis was determined to be the underlying etiology due to subsequent workup revealing polymicrobial gram-negative anaerobic bacteremia and complete thrombosis of the main and left portal veins. To our knowledge, this is the first documented case of acute liver failure as a potential life-threatening complication of pylephlebitis.
CONCLUSION: Our case highlights the importance of considering pylephlebitis in the broad differential for abdominal pain, especially if there are co-existing risk factors for hypercoagulability. We also demonstrate that fulminant hepatic failure in these patients can potentially be reversible with the immediate initiation of antibiotics and anticoagulation.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
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| Enthalten in: |
World journal of hepatology - 16(2024), 1 vom: 27. Jan., Seite 103-108 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Hapshy, Vera [VerfasserIn] |
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| Links: |
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| Themen: |
Acute liver failure |
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| Anmerkungen: |
Date Revised 06.02.2024 published: Print Citation Status PubMed-not-MEDLINE |
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| doi: |
10.4254/wjh.v16.i1.103 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM368024482 |
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| 100 | 1 | |a Hapshy, Vera |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Pylephlebitis-induced acute liver failure |b A case report and review of literature |
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| 500 | |a Date Revised 06.02.2024 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. | ||
| 520 | |a BACKGROUND: Pylephlebitis is an extremely rare form of septic thrombophlebitis involving the portal vein, carrying high rates of morbidity and mortality | ||
| 520 | |a CASE SUMMARY: We present a case of a 42-year-old male with no past medical history who presented with acute onset of abdominal pain and altered mental status with laboratory tests demonstrating new-onset acute liver failure. Pylephlebitis was determined to be the underlying etiology due to subsequent workup revealing polymicrobial gram-negative anaerobic bacteremia and complete thrombosis of the main and left portal veins. To our knowledge, this is the first documented case of acute liver failure as a potential life-threatening complication of pylephlebitis | ||
| 520 | |a CONCLUSION: Our case highlights the importance of considering pylephlebitis in the broad differential for abdominal pain, especially if there are co-existing risk factors for hypercoagulability. We also demonstrate that fulminant hepatic failure in these patients can potentially be reversible with the immediate initiation of antibiotics and anticoagulation | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Acute liver failure | |
| 650 | 4 | |a Case report | |
| 650 | 4 | |a Gram negative anaerobic bacteremia | |
| 650 | 4 | |a Portal vein thrombosis | |
| 650 | 4 | |a Pylephlebitis | |
| 650 | 4 | |a Septic thrombophlebitis | |
| 700 | 1 | |a Imburgio, Steven |e verfasserin |4 aut | |
| 700 | 1 | |a Sanekommu, Harshavardhan |e verfasserin |4 aut | |
| 700 | 1 | |a Nightingale, Brandon |e verfasserin |4 aut | |
| 700 | 1 | |a Taj, Sobaan |e verfasserin |4 aut | |
| 700 | 1 | |a Hossain, Mohammad A |e verfasserin |4 aut | |
| 700 | 1 | |a Patel, Swapnil |e verfasserin |4 aut | |
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