Long-term ambient air pollution and the risk of musculoskeletal diseases : A prospective cohort study
Copyright © 2024 Elsevier B.V. All rights reserved..
Evidence of the associations of air pollution and musculoskeletal diseases is inconsistent. This study aimed to examine the associations between air pollutants and the risk of incident musculoskeletal diseases, such as degenerative joint diseases (n = 38,850) and inflammatory arthropathies (n = 20,108). An air pollution score was constructed to assess the combined effect of PM2.5, PM2.5-10, NO2, and NOX. Cox proportional hazard model was applied to assess the relationships between air pollutants and the incidence of each musculoskeletal disease. The air pollution scores exhibited the modest association with an increased risk of osteoporosis (HR = 1.006, 95% CI: 1.002-1.011). Among the individual air pollutants, PM2.5 and PM2.5-10 exhibited the most significant effect on elevated risk of musculoskeletal diseases, such as PM2.5 on osteoporosis (HR = 1.064, 95% CI: 1.020-1.110), PM2.5-10 on inflammatory arthropathies (HR = 1.059, 95% CI: 1.037-1.081). Females were found to have a higher risk of incident musculoskeletal diseases when exposed to air pollutants. Individuals with extreme BMI or lower socioeconomic status had a higher risk of developing musculoskeletal diseases. Our findings reveal that long-term exposure to ambient air pollutants may contribute to an increased risk of musculoskeletal diseases.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:466 |
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| Enthalten in: |
Journal of hazardous materials - 466(2024) vom: 15. Feb., Seite 133658 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Cheng, Bolun [VerfasserIn] |
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| Links: |
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| Themen: |
Air Pollutants |
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| Anmerkungen: |
Date Completed 14.02.2024 Date Revised 14.02.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.jhazmat.2024.133658 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Evidence of the associations of air pollution and musculoskeletal diseases is inconsistent. This study aimed to examine the associations between air pollutants and the risk of incident musculoskeletal diseases, such as degenerative joint diseases (n = 38,850) and inflammatory arthropathies (n = 20,108). An air pollution score was constructed to assess the combined effect of PM2.5, PM2.5-10, NO2, and NOX. Cox proportional hazard model was applied to assess the relationships between air pollutants and the incidence of each musculoskeletal disease. The air pollution scores exhibited the modest association with an increased risk of osteoporosis (HR = 1.006, 95% CI: 1.002-1.011). Among the individual air pollutants, PM2.5 and PM2.5-10 exhibited the most significant effect on elevated risk of musculoskeletal diseases, such as PM2.5 on osteoporosis (HR = 1.064, 95% CI: 1.020-1.110), PM2.5-10 on inflammatory arthropathies (HR = 1.059, 95% CI: 1.037-1.081). Females were found to have a higher risk of incident musculoskeletal diseases when exposed to air pollutants. Individuals with extreme BMI or lower socioeconomic status had a higher risk of developing musculoskeletal diseases. Our findings reveal that long-term exposure to ambient air pollutants may contribute to an increased risk of musculoskeletal diseases | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Air pollution | |
| 650 | 4 | |a Musculoskeletal diseases | |
| 650 | 4 | |a Prospective cohort | |
| 650 | 4 | |a Socioeconomic status | |
| 650 | 7 | |a Particulate Matter |2 NLM | |
| 650 | 7 | |a Air Pollutants |2 NLM | |
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| 700 | 1 | |a Pan, Chuyu |e verfasserin |4 aut | |
| 700 | 1 | |a Cai, Qingqing |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Li |e verfasserin |4 aut | |
| 700 | 1 | |a Cheng, Shiqiang |e verfasserin |4 aut | |
| 700 | 1 | |a Yang, Xuena |e verfasserin |4 aut | |
| 700 | 1 | |a Meng, Peilin |e verfasserin |4 aut | |
| 700 | 1 | |a Wei, Wenming |e verfasserin |4 aut | |
| 700 | 1 | |a He, Dan |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Huan |e verfasserin |4 aut | |
| 700 | 1 | |a Jia, Yumeng |e verfasserin |4 aut | |
| 700 | 1 | |a Wen, Yan |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Peng |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Feng |e verfasserin |4 aut | |
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