Effective Strategies in Designing Chitosan-hyaluronic Acid Nanocarriers : From Synthesis to Drug Delivery Towards Chemotherapy

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The biomedical field faces an ongoing challenge in developing more effective anti-cancer medication due to the significant burden that cancer poses on human health. Extensive research has been conducted on the utilization of natural polysaccharides in nanomedicine owing to their properties of biocompatibility, biodegradability, non-immunogenicity, and non-toxicity. These characteristics make them a potent drug delivery system for cancer therapy. The chitosan hyaluronic acid nanoparticle (CSHANp) system, consisting of chitosan and hyaluronic acid nanoparticles, has exhibited considerable potential as a nanocarrier for various cancer drugs, rendering it one of the most auspicious systems presently accessible. The CSHANps demonstrate remarkable drug loading capacity, precise control over drug release, and exceptional selectivity towards cancer cells. These properties enhance the therapeutic effectiveness against cancerous cells. This article aims to provide a comprehensive analysis of CSHANp, focusing on its characteristics, production techniques, applications, and future prospects.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Current drug delivery - (2024) vom: 16. Jan.

Sprache:

Englisch

Beteiligte Personen:

Hong, Long-Quy [VerfasserIn]
Ho, Thao N T [VerfasserIn]
Cu, Son T [VerfasserIn]
Tuyet Ngan, Lien [VerfasserIn]
Ngoc Quyen, Tran [VerfasserIn]
Dang, Tien T [VerfasserIn]

Links:

Volltext

Themen:

Cancer
Chitosan
Cyclotide
Hyaluronic acid
Journal Article
Nanocarrier
Nanoparticle

Anmerkungen:

Date Revised 04.02.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.2174/0115672018275983231207101222

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM367999218