Intelligent Drug Delivery : Pioneering Stimuli-Responsive Systems to Revolutionize Disease Management- An In-depth Exploration

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In recent years, there has been an escalating interest in stimuli-responsive drug delivery systems (SRDDS) due to their ability to revolutionize the delivery of therapeutics. SRDDSs offer a multitude of benefits in comparison to conventional drug delivery systems (DDS), including spatiotemporal control of drug release, targeted delivery, and improved therapeutic efficacy. The development of various classes of stimuli-responsive DDS, such as pH-responsive, temperature-responsive, photo-responsive, redox responsive systems, has been propelled by advances in materials science, nanotechnology, and biotechnology. These systems exploit specific environmental or physiological cues to trigger drug release in a precisely controlled manner, making them highly promising for the treatment of various diseases. In this review article, an in-depth exploration of the principles, mechanisms, and applications of SRDDS in the context of diverse pathologies such as cancer, arthritis, Alzheimer's disease, atherosclerosis and tissue engineering has been provided. Furthermore, this article delves into the discussion of recent patents, market overview and the progress of research in clinical trials. Overall, this article underscores the transformative potential of SRDDS in enabling personalized, precise, and effective drug delivery for the treatment of the above-mentioned diseases.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Current drug delivery - (2024) vom: 26. Jan.

Sprache:

Englisch

Beteiligte Personen:

Kallepalli, Badarinadh [VerfasserIn]
Garg, Unnati [VerfasserIn]
Jain, Neha [VerfasserIn]
Nagpal, Rohan [VerfasserIn]
Malhotra, Sakshi [VerfasserIn]
Tiwari, Triveni [VerfasserIn]
Kaul, Shreya [VerfasserIn]
Nagaich, Upendra [VerfasserIn]

Links:

Volltext

Themen:

Chemical-responsive drug delivery systems
Intelligent Polymers
Intelligent biomaterials
Journal Article
Physical-responsive drug delivery systems
SRDDS market overview
Stimuli-responsive drug delivery systems (SRDDS)

Anmerkungen:

Date Revised 04.02.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.2174/0115672018278641231221051359

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM36799917X