Effect of Flavonoids against Parkinson's Disease

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Parkinson's disease (PD) is the second most common neurodegenerative disorder. It is characterized by the depletion of striatal dopamine content and aggregation of alphasynuclein in the substantia nigra (SN). It is possible to treat the symptoms of PD with a variety of medications, but they often result in complications and are not able to cure or stop the progression of the disease. Flavonoids (the phytocomponents present in almost all fruits and vegetables) are the class of secondary metabolites that have generated a peak of interest because of their medicinal properties, including a reduction in the risk of PD. Several flavonoids such as quercetin, kaempferol, hesperitin, anthocyanin and many more have been reported for their anti- Parkinson's effect. This review deals with the neuroprotective benefits of different classes of flavonoids against PD.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Central nervous system agents in medicinal chemistry - (2024) vom: 16. Jan.

Sprache:

Englisch

Beteiligte Personen:

Varshney, Himanshi [VerfasserIn]
Siddique, Yasir Hasan [VerfasserIn]

Links:

Volltext

Themen:

Flavonoids
Journal Article
Neurodegenerative disorders.
Oxidative stress
Parkinson's disease

Anmerkungen:

Date Revised 02.02.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.2174/0118715249264078231214074107

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM367947595