A Case of HER2-Positive Unresectable Advanced Gastric Cancer Showing Long-Term Complete Response Treated by Only Chemotherapy
A 78-year-old man was diagnosed as HER2-positive unresectable advanced gastric cancer(cT4aN3M1[LYM], Stage Ⅳ). After 2 courses of first-line chemotherapy(S-1 plus oxaliplatin plus trastuzumab), PR was achieved. The treatment could not be continued due to adverse events after 5 courses, thus second-line chemotherapy was conducted. Corresponding to the physical condition. The third-line chemotherapy was also introduced. However, we clinically judged PD because of amount of ascites and chemotherapy was terminated. After that, he has survived for more than 2 years without chemotherapy, and endoscopy and CT showed the disappearance of the tumor, metastatic lymph nodes, and ascites at 41 months after diagnosis. Looking back on the changes in tumor markers, it was possible that he had already achieved CR at the first-line chemotherapy.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:50 |
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| Enthalten in: |
Gan to kagaku ryoho. Cancer & chemotherapy - 50(2023), 13 vom: 02. Dez., Seite 1887-1888 |
| Sprache: |
Japanisch |
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| Beteiligte Personen: |
Shirasaki, Yumi [VerfasserIn] |
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| Themen: |
Case Reports |
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| Anmerkungen: |
Date Completed 06.02.2024 Date Revised 06.02.2024 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM367926024 |
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| 245 | 1 | 2 | |a A Case of HER2-Positive Unresectable Advanced Gastric Cancer Showing Long-Term Complete Response Treated by Only Chemotherapy |
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| 500 | |a Date Completed 06.02.2024 | ||
| 500 | |a Date Revised 06.02.2024 | ||
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a A 78-year-old man was diagnosed as HER2-positive unresectable advanced gastric cancer(cT4aN3M1[LYM], Stage Ⅳ). After 2 courses of first-line chemotherapy(S-1 plus oxaliplatin plus trastuzumab), PR was achieved. The treatment could not be continued due to adverse events after 5 courses, thus second-line chemotherapy was conducted. Corresponding to the physical condition. The third-line chemotherapy was also introduced. However, we clinically judged PD because of amount of ascites and chemotherapy was terminated. After that, he has survived for more than 2 years without chemotherapy, and endoscopy and CT showed the disappearance of the tumor, metastatic lymph nodes, and ascites at 41 months after diagnosis. Looking back on the changes in tumor markers, it was possible that he had already achieved CR at the first-line chemotherapy | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Wada, Noriko |e verfasserin |4 aut | |
| 700 | 1 | |a Takachi, Ko |e verfasserin |4 aut | |
| 700 | 1 | |a Fujiwara, Masataka |e verfasserin |4 aut | |
| 700 | 1 | |a Fukuda, Nijie |e verfasserin |4 aut | |
| 700 | 1 | |a Matsuura, Yusuke |e verfasserin |4 aut | |
| 700 | 1 | |a Munakata, Koji |e verfasserin |4 aut | |
| 700 | 1 | |a Takiuchi, Daisuke |e verfasserin |4 aut | |
| 700 | 1 | |a Hama, Naoki |e verfasserin |4 aut | |
| 700 | 1 | |a Ota, Hirofumi |e verfasserin |4 aut | |
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