Gut Microbiota and Neonatal Acute Kidney Injury

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OBJECTIVE:  To characterize the relationship between gut microbiota and neonatal acute kidney injury biomarkers based on the gut-kidney axis.

STUDY DESIGN:  The Pubmed database was primarily searched to include relevant literature on gut microbiota and neonatal acute kidney injury biomarkers, which was subsequently organized and analyzed and a manuscript was written.

RESULTS:  Gut microbiota was associated with neonatal acute kidney injury biomarkers. These biomarkers included TIMP-2, IGFBP-7, VEGF, calbindin, GST, B2MG, ghrelin, and clusterin.

CONCLUSION:  The gut microbiota is strongly associated with neonatal acute kidney injury biomarkers, and controlling the gut microbiota may be a potential target for ameliorating neonatal acute kidney injury.

KEY POINTS: · There is a bidirectional association between gut microbiota and AKI.. · Gut microbiota is closely associated with biomarkers of nAKI.. · Manipulation of gut microbiota may improve nAKI.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

American journal of perinatology - (2024) vom: 26. Feb.

Sprache:

Englisch

Beteiligte Personen:

Yang, Kun [VerfasserIn]
He, Hongxia [VerfasserIn]
Dong, Wenbin [VerfasserIn]

Links:

Volltext

Themen:

Journal Article

Anmerkungen:

Date Revised 26.02.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.1055/a-2259-0101

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM36791087X