Effect of Prevalence and Severity of Molar-Incisor Hypomineralization on Oral Health-Related Quality of Life : A Systematic Review and Meta-Analysis
University of Zagreb School of Dental Medicine..
Objectives: The aim of this systematic review and meta-analysis is to assess the association between the MIH presence as well as the severity and OHRQoL in children.
Material and methods: Relevant studies were identified in PubMed, Embase, Cochrane and Google Scholar. Studies involving MIH and OHRQoL in children were included. A methodological quality assessment of included studies was performed using the Newcastle-Ottawa Scale (NOS) and its adapted version for cross-sectional studies. Random effects models were used to estimate summary effect measures for the association between MIH presence (presence vs. absence) as well as severity (moderate/severe MIH vs. no MIH) and OHRQoL using generic inverse variance meta-analyses. Tests for heterogeneity, publication bias and sensitivity of results were also performed.
Results: Out of 1696 identified publications 11 studies reporting on 5,017 children were included in the meta-analysis assessing the impact of MIH presence. There was no statistically significant association between the presence of MIH and lower OHRQoL in affected children (OR = 1.72, 95% CI = 0.99-2.98). Concerning MIH severity and its impact on OHRQoL, a sum of 6 studies were included in the meta-analysis involving a total of 2,595 children. There was a significant association between moderate/severe MIH and lower OHRQoL in affected children (OR = 3.43, 95% CI = 1.69-6.98).
Conclusion: Moderate/Severe MIH has a significant and clinically relevant negative impact on OHRQoL, and it should therefore be addressed adequately. Future research should also consider the impact of a uniform MIH diagnosis and precise severity criteria.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:57 |
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| Enthalten in: |
Acta stomatologica Croatica - 57(2023), 4 vom: 15. Dez., Seite 381-394 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Awwad, Abdelrahman [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Revised 31.01.2024 published: Print Citation Status PubMed-not-MEDLINE |
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| doi: |
10.15644/asc57/4/8 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM367737256 |
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| 245 | 1 | 0 | |a Effect of Prevalence and Severity of Molar-Incisor Hypomineralization on Oral Health-Related Quality of Life |b A Systematic Review and Meta-Analysis |
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| 500 | |a Date Revised 31.01.2024 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a University of Zagreb School of Dental Medicine. | ||
| 520 | |a Objectives: The aim of this systematic review and meta-analysis is to assess the association between the MIH presence as well as the severity and OHRQoL in children | ||
| 520 | |a Material and methods: Relevant studies were identified in PubMed, Embase, Cochrane and Google Scholar. Studies involving MIH and OHRQoL in children were included. A methodological quality assessment of included studies was performed using the Newcastle-Ottawa Scale (NOS) and its adapted version for cross-sectional studies. Random effects models were used to estimate summary effect measures for the association between MIH presence (presence vs. absence) as well as severity (moderate/severe MIH vs. no MIH) and OHRQoL using generic inverse variance meta-analyses. Tests for heterogeneity, publication bias and sensitivity of results were also performed | ||
| 520 | |a Results: Out of 1696 identified publications 11 studies reporting on 5,017 children were included in the meta-analysis assessing the impact of MIH presence. There was no statistically significant association between the presence of MIH and lower OHRQoL in affected children (OR = 1.72, 95% CI = 0.99-2.98). Concerning MIH severity and its impact on OHRQoL, a sum of 6 studies were included in the meta-analysis involving a total of 2,595 children. There was a significant association between moderate/severe MIH and lower OHRQoL in affected children (OR = 3.43, 95% CI = 1.69-6.98) | ||
| 520 | |a Conclusion: Moderate/Severe MIH has a significant and clinically relevant negative impact on OHRQoL, and it should therefore be addressed adequately. Future research should also consider the impact of a uniform MIH diagnosis and precise severity criteria | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Child Author Keywords: Molar Incisor Hypomineralization | |
| 650 | 4 | |a MeSH Terms: Molar Hypomineralization | |
| 650 | 4 | |a Molar Incisor Hypomineralization | |
| 650 | 4 | |a Oral Health-Related Quality of Life | |
| 650 | 4 | |a Oral HealthRelated Quality of Life | |
| 650 | 4 | |a Pediatric Dentistry | |
| 650 | 4 | |a Quality of Life | |
| 650 | 4 | |a Systematic Review | |
| 700 | 1 | |a Hamad, Rakan |e verfasserin |4 aut | |
| 700 | 1 | |a Schiffner, Ulrich |e verfasserin |4 aut | |
| 700 | 1 | |a Splieth, Christian H |e verfasserin |4 aut | |
| 700 | 1 | |a Schmoeckel, Julian |e verfasserin |4 aut | |
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| 773 | 1 | 8 | |g volume:57 |g year:2023 |g number:4 |g day:15 |g month:12 |g pages:381-394 |
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