Therapeutic plasma exchange for neuromyelitis optica attacks : Evidence and challenges from a real-world cohort from Brazil
Copyright © 2024 Elsevier B.V. All rights reserved..
Therapeutic plasma exchange (TPE) can improve disability recovery after neuromyelitis optica spectrum disease (NMOSD) attacks, but its effectiveness and safety in Latin-American patients with access barriers and diverse ethnicity is underexplored. We carried out a retrospective cohort study with NMOSD patients that underwent TPE. 84 NMOSD attacks in 68 patients were evaluated. Despite a median 25-day delay from symptom onset to TPE, 65,5% of patients showed significant improvement. Adverse events occurred in 39% of patients, usually transitory and with no fatalities.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:388 |
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| Enthalten in: |
Journal of neuroimmunology - 388(2024) vom: 15. März, Seite 578295 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
de Almeida, Guilherme Mello Ramos [VerfasserIn] |
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| Links: |
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| Themen: |
Aquaporin 4 |
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| Anmerkungen: |
Date Completed 08.03.2024 Date Revised 21.03.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.jneuroim.2024.578295 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Therapeutic plasma exchange (TPE) can improve disability recovery after neuromyelitis optica spectrum disease (NMOSD) attacks, but its effectiveness and safety in Latin-American patients with access barriers and diverse ethnicity is underexplored. We carried out a retrospective cohort study with NMOSD patients that underwent TPE. 84 NMOSD attacks in 68 patients were evaluated. Despite a median 25-day delay from symptom onset to TPE, 65,5% of patients showed significant improvement. Adverse events occurred in 39% of patients, usually transitory and with no fatalities | ||
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Fortini, Ida |e verfasserin |4 aut | |
| 700 | 1 | |a Gonçalves, Marcia Rubia Rodrigues |e verfasserin |4 aut | |
| 700 | 1 | |a Castro, Luiz Henrique Martins |e verfasserin |4 aut | |
| 700 | 1 | |a Tatsui, Nelson Hidekazu |e verfasserin |4 aut | |
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| 700 | 1 | |a Apóstolos-Pereira, Samira Luísa |e verfasserin |4 aut | |
| 700 | 1 | |a Callegaro, Dagoberto |e verfasserin |4 aut | |
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