Emerging treatment options for skin and soft tissue infections tailoring drug selection to individual patients

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PURPOSE OF REVIEW: To provide a brief overview of drugs in Phase II and III of development for the treatment of acute bacterial skin and skin structure infections (ABSSSI), offering insights into potential customized treatment options.

RECENT FINDINGS: Several drugs are currently in advanced stages of evaluation for the treatment of ABSSSI, and numerous molecules are entering in the early development phases. Notably, many of these drugs exhibit unique mechanisms of action and interesting antimicrobial spectrum.

SUMMARY: Tailoring antibiotic therapy based on patient characteristics, likely pathogens, type, site and severity of ABSSSI is crucial. Given the inherent limitations of available treatments, the development of novel agents is a pivotal avenue. Such advancements hold promise for enhancing treatment efficacy and simplifying drug selection for ABSSSI in everyday clinical practice.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:37

Enthalten in:

Current opinion in infectious diseases - 37(2024), 2 vom: 01. Feb., Seite 80-86

Sprache:

Englisch

Beteiligte Personen:

Castaldo, Nadia [VerfasserIn]
Vena, Antonio [VerfasserIn]
Limongelli, Alessandro [VerfasserIn]
Giacobbe, Daniele Roberto [VerfasserIn]
Bassetti, Matteo [VerfasserIn]

Links:

Volltext

Themen:

Anti-Bacterial Agents
Journal Article
Review

Anmerkungen:

Date Completed 28.02.2024

Date Revised 28.02.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1097/QCO.0000000000001003

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM367675854