A Severe Case of Isotretinoin Induced Eosinophilic Pneumonia and Pericardial Effusion, a Case Report
Copyright© Bentham Science Publishers; For any queries, please email at epubbenthamscience.net..
BACKGROUND: We report a case of a 25-year-old female who presented with fever, rash and general malaise.
CASE PRESENTATION: She was initially diagnosed and treated for peri-/myocarditis, but she deteriorated quickly with the development of extensive bilateral consolidations for which she was mechanically ventilated. Two weeks before admission, she took isotretinoin for less than a week for disfiguring acne. Diagnosis of drug-induced acute eosinophilic pneumoniae (EP) was made after excluding other causes of AEP. Even before starting steroid treatment, the patient improved significantly, which was in alignment with the elimination of the active metabolite of isotretinoin.
CONCLUSION: The presented case underlines the importance of performing a thorough history and consider recently started drugs as the cause of eosinophilic pneumoniae, even if they have not yet been described as a known trigger of drug-induced EP.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Current drug safety - (2024) vom: 24. Jan. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kampman, Anne [VerfasserIn] |
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| Links: |
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| Themen: |
Care report |
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| Anmerkungen: |
Date Revised 26.01.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.2174/0115748863274642231121072432 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM367654660 |
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| 100 | 1 | |a Kampman, Anne |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A Severe Case of Isotretinoin Induced Eosinophilic Pneumonia and Pericardial Effusion, a Case Report |
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| 500 | |a Date Revised 26.01.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a Copyright© Bentham Science Publishers; For any queries, please email at epubbenthamscience.net. | ||
| 520 | |a BACKGROUND: We report a case of a 25-year-old female who presented with fever, rash and general malaise | ||
| 520 | |a CASE PRESENTATION: She was initially diagnosed and treated for peri-/myocarditis, but she deteriorated quickly with the development of extensive bilateral consolidations for which she was mechanically ventilated. Two weeks before admission, she took isotretinoin for less than a week for disfiguring acne. Diagnosis of drug-induced acute eosinophilic pneumoniae (EP) was made after excluding other causes of AEP. Even before starting steroid treatment, the patient improved significantly, which was in alignment with the elimination of the active metabolite of isotretinoin | ||
| 520 | |a CONCLUSION: The presented case underlines the importance of performing a thorough history and consider recently started drugs as the cause of eosinophilic pneumoniae, even if they have not yet been described as a known trigger of drug-induced EP | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Care report | |
| 650 | 4 | |a Drug induced eosinophilic pneumonia | |
| 650 | 4 | |a Eosinophilic pneumonia | |
| 650 | 4 | |a Hypersensitivity reaction | |
| 650 | 4 | |a Isotretinoin | |
| 650 | 4 | |a Pericardial effusion | |
| 700 | 1 | |a Keulers, Laurien |e verfasserin |4 aut | |
| 700 | 1 | |a der Maten, Jan van |e verfasserin |4 aut | |
| 700 | 1 | |a der Meij, Jacqueline van |e verfasserin |4 aut | |
| 700 | 1 | |a Bethlehem, Carina |e verfasserin |4 aut | |
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