The Rise of Adaptive Platform Trials in Critical Care
As durable learning research systems, adaptive platform trials represent a transformative new approach to accelerating clinical evaluation and discovery in critical care. This Perspective provides a brief introduction to the concept of adaptive platform trials, describes several established and emerging platforms in critical care, and surveys some opportunities and challenges for their implementation and impact.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:209 |
|---|---|
| Enthalten in: |
American journal of respiratory and critical care medicine - 209(2024), 5 vom: 01. März, Seite 491-496 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
PRACTICAL, PANTHER, TRAITS, INCEPT, and REMAP-CAP investigators [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 04.03.2024 Date Revised 09.03.2024 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.1164/rccm.202401-0101CP |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM367620405 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM367620405 | ||
| 003 | DE-627 | ||
| 005 | 20240309232159.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240126s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1164/rccm.202401-0101CP |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1321.xml |
| 035 | |a (DE-627)NLM367620405 | ||
| 035 | |a (NLM)38271622 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 0 | |a PRACTICAL, PANTHER, TRAITS, INCEPT, and REMAP-CAP investigators |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The Rise of Adaptive Platform Trials in Critical Care |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 04.03.2024 | ||
| 500 | |a Date Revised 09.03.2024 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a As durable learning research systems, adaptive platform trials represent a transformative new approach to accelerating clinical evaluation and discovery in critical care. This Perspective provides a brief introduction to the concept of adaptive platform trials, describes several established and emerging platforms in critical care, and surveys some opportunities and challenges for their implementation and impact | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a adaptive design | |
| 650 | 4 | |a critical care | |
| 650 | 4 | |a platform trials | |
| 700 | 1 | |a Bos, Lieuwe D J |e investigator |4 oth | |
| 700 | 1 | |a Calfee, Carolyn |e investigator |4 oth | |
| 700 | 1 | |a Castellvi-Font, Andrea |e investigator |4 oth | |
| 700 | 1 | |a Cornelius, Victoria |e investigator |4 oth | |
| 700 | 1 | |a Derde, Lennie P G |e investigator |4 oth | |
| 700 | 1 | |a Docherty, Annemarie |e investigator |4 oth | |
| 700 | 1 | |a Fan, Eddy |e investigator |4 oth | |
| 700 | 1 | |a Ferguson, Niall |e investigator |4 oth | |
| 700 | 1 | |a Goligher, Ewan C |e investigator |4 oth | |
| 700 | 1 | |a Gordon, Anthony C |e investigator |4 oth | |
| 700 | 1 | |a Granholm, Anders |e investigator |4 oth | |
| 700 | 1 | |a Harhay, Michael O |e investigator |4 oth | |
| 700 | 1 | |a Heath, Anna |e investigator |4 oth | |
| 700 | 1 | |a Nørregaard Kjær, Maj-Brit |e investigator |4 oth | |
| 700 | 1 | |a Lawler, Patrick R |e investigator |4 oth | |
| 700 | 1 | |a Lone, Nazir |e investigator |4 oth | |
| 700 | 1 | |a McAuley, Danny |e investigator |4 oth | |
| 700 | 1 | |a Møller, Morten Hylander |e investigator |4 oth | |
| 700 | 1 | |a Munshi, Laveena |e investigator |4 oth | |
| 700 | 1 | |a Murthy, Srinivas |e investigator |4 oth | |
| 700 | 1 | |a Nichol, Alistair D |e investigator |4 oth | |
| 700 | 1 | |a Perner, Anders |e investigator |4 oth | |
| 700 | 1 | |a Reddy, Kiran |e investigator |4 oth | |
| 700 | 1 | |a Rochwerg, Bram |e investigator |4 oth | |
| 700 | 1 | |a Rowan, Kathy |e investigator |4 oth | |
| 700 | 1 | |a Sahetya, Sarina |e investigator |4 oth | |
| 700 | 1 | |a Shankar-Hari, Manu |e investigator |4 oth | |
| 700 | 1 | |a Webb, Steve |e investigator |4 oth | |
| 700 | 1 | |a Weir, Christopher |e investigator |4 oth | |
| 700 | 1 | |a Zarychanski, Ryan |e investigator |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t American journal of respiratory and critical care medicine |d 1994 |g 209(2024), 5 vom: 01. März, Seite 491-496 |w (DE-627)NLM074657305 |x 1535-4970 |7 nnns |
| 773 | 1 | 8 | |g volume:209 |g year:2024 |g number:5 |g day:01 |g month:03 |g pages:491-496 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1164/rccm.202401-0101CP |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 209 |j 2024 |e 5 |b 01 |c 03 |h 491-496 | ||