Somatic multicomorbidity and disability in patients with psychiatric disorders in comparison to the general population : a quasi-epidemiological investigation in 54,826 subjects from 40 countries (COMET-G study)

BACKGROUND: The prevalence of medical illnesses is high among patients with psychiatric disorders. The current study aimed to investigate multi-comorbidity in patients with psychiatric disorders in comparison to the general population. Secondary aims were to investigate factors associated with metabolic syndrome and treatment appropriateness of mental disorders.

METHODS: The sample included 54,826 subjects (64.73% females; 34.15% males; 1.11% nonbinary gender) from 40 countries (COMET-G study). The analysis was based on the registration of previous history that could serve as a fair approximation for the lifetime prevalence of various medical conditions.

RESULTS: About 24.5% reported a history of somatic and 26.14% of mental disorders. Mental disorders were by far the most prevalent group of medical conditions. Comorbidity of any somatic with any mental disorder was reported by 8.21%. One-third to almost two-thirds of somatic patients were also suffering from a mental disorder depending on the severity and multicomorbidity. Bipolar and psychotic patients and to a lesser extent depressives, manifested an earlier (15-20 years) manifestation of somatic multicomorbidity, severe disability, and probably earlier death. The overwhelming majority of patients with mental disorders were not receiving treatment or were being treated in a way that was not recommended. Antipsychotics and antidepressants were not related to the development of metabolic syndrome.

CONCLUSIONS: The finding that one-third to almost two-thirds of somatic patients also suffered from a mental disorder strongly suggests that psychiatry is the field with the most trans-specialty and interdisciplinary value and application points to the importance of teaching psychiatry and mental health in medical schools and also to the need for more technocratically oriented training of psychiatric residents.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:29

Enthalten in:

CNS spectrums - 29(2024), 2 vom: 01. Apr., Seite 126-149

Sprache:

Englisch

Beteiligte Personen:

Fountoulakis, Konstantinos N [VerfasserIn]
Karakatsoulis, Grigorios N [VerfasserIn]
Abraham, Seri [VerfasserIn]
Adorjan, Kristina [VerfasserIn]
Ahmed, Helal Uddin [VerfasserIn]
Alarcón, Renato D [VerfasserIn]
Arai, Kiyomi [VerfasserIn]
Auwal, Sani Salihu [VerfasserIn]
Berk, Michael [VerfasserIn]
Bjedov, Sarah [VerfasserIn]
Bobes, Julio [VerfasserIn]
Bobes-Bascaran, Teresa [VerfasserIn]
Bourgin-Duchesnay, Julie [VerfasserIn]
Bredicean, Cristina Ana [VerfasserIn]
Bukelskis, Laurynas [VerfasserIn]
Burkadze, Akaki [VerfasserIn]
Cabrera Abud, Indira Indiana [VerfasserIn]
Castilla-Puentes, Ruby [VerfasserIn]
Cetkovich, Marcelo [VerfasserIn]
Colon-Rivera, Hector [VerfasserIn]
Corral, Ricardo [VerfasserIn]
Cortez-Vergara, Carla [VerfasserIn]
Crepin, Piirika [VerfasserIn]
De Berardis, Domenico [VerfasserIn]
Zamora Delgado, Sergio [VerfasserIn]
Lucena, David De [VerfasserIn]
Sousa, Avinash De [VerfasserIn]
Stefano, Ramona Di [VerfasserIn]
Dodd, Seetal [VerfasserIn]
Priyanka Elek, Livia [VerfasserIn]
Elissa, Anna [VerfasserIn]
Erdelyi-Hamza, Berta [VerfasserIn]
Erzin, Gamze [VerfasserIn]
Etchevers, Martin J [VerfasserIn]
Falkai, Peter [VerfasserIn]
Farcas, Adriana [VerfasserIn]
Fedotov, Ilya [VerfasserIn]
Filatova, Viktoriia [VerfasserIn]
Fountoulakis, Nikolaos K [VerfasserIn]
Frankova, Iryna [VerfasserIn]
Franza, Francesco [VerfasserIn]
Frias, Pedro [VerfasserIn]
Galako, Tatiana [VerfasserIn]
Garay, Cristian J [VerfasserIn]
Garcia-Álvarez, Leticia [VerfasserIn]
García-Portilla, Maria Paz [VerfasserIn]
Gonda, Xenia [VerfasserIn]
Gondek, Tomasz M [VerfasserIn]
Morera González, Daniela [VerfasserIn]
Gould, Hilary [VerfasserIn]
Grandinetti, Paolo [VerfasserIn]
Grau, Arturo [VerfasserIn]
Groudeva, Violeta [VerfasserIn]
Hagin, Michal [VerfasserIn]
Harada, Takayuki [VerfasserIn]
Hasan, Tasdik M [VerfasserIn]
Azreen Hashim, Nurul [VerfasserIn]
Hilbig, Jan [VerfasserIn]
Hossain, Sahadat [VerfasserIn]
Iakimova, Rossitza [VerfasserIn]
Ibrahim, Mona [VerfasserIn]
Iftene, Felicia [VerfasserIn]
Ignatenko, Yulia [VerfasserIn]
Irarrazaval, Matias [VerfasserIn]
Ismail, Zaliha [VerfasserIn]
Ismayilova, Jamila [VerfasserIn]
Jakobs, Asaf [VerfasserIn]
Jakovljević, Miro [VerfasserIn]
Jakšić, Nenad [VerfasserIn]
Javed, Afzal [VerfasserIn]
Kafali, Helin Yilmaz [VerfasserIn]
Karia, Sagar [VerfasserIn]
Kazakova, Olga [VerfasserIn]
Khalifa, Doaa [VerfasserIn]
Khaustova, Olena [VerfasserIn]
Koh, Steve [VerfasserIn]
Kopishinskaia, Svetlana [VerfasserIn]
Kosenko, Korneliia [VerfasserIn]
Koupidis, Sotirios A [VerfasserIn]
Kovacs, Illes [VerfasserIn]
Kulig, Barbara [VerfasserIn]
Lalljee, Alisha [VerfasserIn]
Liewig, Justine [VerfasserIn]
Majid, Abdul [VerfasserIn]
Malashonkova, Evgeniia [VerfasserIn]
Malik, Khamelia [VerfasserIn]
Malik, Najma Iqbal [VerfasserIn]
Mammadzada, Gulay [VerfasserIn]
Mandalia, Bilvesh [VerfasserIn]
Marazziti, Donatella [VerfasserIn]
Marčinko, Darko [VerfasserIn]
Martinez, Stephanie [VerfasserIn]
Matiekus, Eimantas [VerfasserIn]
Mejia, Gabriela [VerfasserIn]
Memon, Roha Saeed [VerfasserIn]
Meza Martínez, Xarah Elenne [VerfasserIn]
Mickevičiūtė, Dalia [VerfasserIn]
Milev, Roumen [VerfasserIn]
Mohammed, Muftau [VerfasserIn]
Molina-López, Alejandro [VerfasserIn]
et al [Sonstige Person]

Links:

Volltext

Themen:

Antipsychotic Agents
Disability
Epidemiology
Journal Article
Multicomorbidity
Premature death
Somatic-mental comorbidity

Anmerkungen:

Date Completed 12.04.2024

Date Revised 19.04.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1017/S1092852924000026

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM367599961