Evaluation and treatment of constipation in pregnancy:Examination using the Japanese version of the constipation evaluation scale
OBJECTIVES: No study has examined the effects of new constipation treatment drugs released in recent years in pregnant women. This prospective cohort study aimed to examine and compare the perinatal prognosis, efficacy rate, and safety of drugs frequently used to treat constipation.
METHODS: The study included 211 perinatally managed individuals who answered a self-administered questionnaire during the second trimester and after delivery. The Japanese version of the constipation evaluation scale (Constipation Assessment Scale [CAS] long-term [LT] version) was used for the subjective evaluation of defecation status.
RESULTS: Participants aware of constipation had significantly higher CAS scores than those who were unaware. Some participants with a CAS score of 5 points (treatment range) had no subjective symptoms of constipation, whereas some participants with a CAS score of ≤ 5 points were aware of constipation. Regarding the time of onset, 60% of those who had constipation before pregnancy had a high rate of constipation during pregnancy and after delivery. No significant difference was noted in conventional magnesium oxide and polyethylene glycol, a relatively new daily treatment drug, in perinatal prognosis or side effects.
CONCLUSIONS: Polyethylene glycol preparations alleviate constipation without inducing diarrhea, making them an appropriate therapeutic option for pregnant women.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:70 |
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| Enthalten in: |
Fukushima journal of medical science - 70(2024), 1 vom: 27. Jan., Seite 35-47 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ishibashi, Makiho [VerfasserIn] |
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| Links: |
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| Themen: |
3WJQ0SDW1A |
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| Anmerkungen: |
Date Completed 30.01.2024 Date Revised 17.02.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.5387/fms.2023-25 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM367574586 |
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| 100 | 1 | |a Ishibashi, Makiho |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Evaluation and treatment of constipation in pregnancy:Examination using the Japanese version of the constipation evaluation scale |
| 264 | 1 | |c 2024 | |
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| 500 | |a Date Completed 30.01.2024 | ||
| 500 | |a Date Revised 17.02.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVES: No study has examined the effects of new constipation treatment drugs released in recent years in pregnant women. This prospective cohort study aimed to examine and compare the perinatal prognosis, efficacy rate, and safety of drugs frequently used to treat constipation | ||
| 520 | |a METHODS: The study included 211 perinatally managed individuals who answered a self-administered questionnaire during the second trimester and after delivery. The Japanese version of the constipation evaluation scale (Constipation Assessment Scale [CAS] long-term [LT] version) was used for the subjective evaluation of defecation status | ||
| 520 | |a RESULTS: Participants aware of constipation had significantly higher CAS scores than those who were unaware. Some participants with a CAS score of 5 points (treatment range) had no subjective symptoms of constipation, whereas some participants with a CAS score of ≤ 5 points were aware of constipation. Regarding the time of onset, 60% of those who had constipation before pregnancy had a high rate of constipation during pregnancy and after delivery. No significant difference was noted in conventional magnesium oxide and polyethylene glycol, a relatively new daily treatment drug, in perinatal prognosis or side effects | ||
| 520 | |a CONCLUSIONS: Polyethylene glycol preparations alleviate constipation without inducing diarrhea, making them an appropriate therapeutic option for pregnant women | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Constipation | |
| 650 | 4 | |a pregnancy | |
| 650 | 4 | |a prospective study | |
| 650 | 4 | |a treatment | |
| 650 | 7 | |a Polyethylene Glycols |2 NLM | |
| 650 | 7 | |a 3WJQ0SDW1A |2 NLM | |
| 700 | 1 | |a Hashimoto, Fumie |e verfasserin |4 aut | |
| 700 | 1 | |a Kouchi, Yoshihiro |e verfasserin |4 aut | |
| 700 | 1 | |a Imaizumi, Karin |e verfasserin |4 aut | |
| 700 | 1 | |a Ito, Fumihiro |e verfasserin |4 aut | |
| 700 | 1 | |a Yasuda, Shun |e verfasserin |4 aut | |
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