Performance of dual-layer spectrum CT virtual monoenergetic images to assess early rectal adenocarcinoma T-stage : comparison with MR
© 2024. The Author(s)..
OBJECTIVES: To evaluate the image quality and utility of virtual monoenergetic images (VMI) of dual-layer spectrum computed tomography (DLSCT) in assessing preoperative T-stage for early rectal adenocarcinoma (ERA).
METHODS: This retrospective study included 67 ERA patients (mean age 62 ± 11.1 years) who underwent DLSCT and MR examination. VMI 40-200 keV and poly energetic image (PEI) were reconstructed. The image noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and tumor contrast of different energy levels were calculated and compared, respectively. Two radiologists independently assess the image quality of the VMIs and PEI using 5-point scales. The diagnostic accuracies of DLSCT and HR-MRI for ERA T-staging were evaluated and compared.
RESULTS: The maximum noise was observed at VMI 40 keV, and noise at VMI 40-200 keV in the arterial and venous phases showed no significant difference (all p > 0.05). The highest SNR and CNR were obtained at VMI 40 keV, significantly greater than other energy levels and PEI (all p < 0.05). Tumor contrast was more evident than PEI at 40-100 keV in the arterial phase and at 40 keV in the venous phase (all p < 0.05). When compared with PEI, VMI 40 keV yielded the highest scores for overall image quality, tumor visibility, and tumor margin delineation, especially in the venous phase (p < 0.05). The overall diagnostic accuracy of DLSCT and HR-MRI for T-stage was 65.67 and 71.64% and showed no significant difference (p > 0.05).
CONCLUSIONS: VMI 40 keV improves image quality and accuracy in identifying lesions, providing better diagnostic information for ERA staging.
CRITICAL RELEVANCE STATEMENT: Low-keV VMI from DLSCT can improve tumor staging accuracy for early rectal carcinoma, helping guide surgical intervention decisions, and has shed new light on the potential breakthroughs of assessing preoperative T-stage in RC.
KEYPOINTS: • Compared with PEI, low-keV VIM derived from DLSCT, particularly at the 40 keV, significantly enhanced the objective and subjective image quality of ERA. • Using VMI 40 keV helped increase lesion detectability, leading to improved diagnostic accuracy for ERA. • Low-keV VMI from DLSCT has shed new light on the potential breakthroughs of assessing preoperative T-stage in RC.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:15 |
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| Enthalten in: |
Insights into imaging - 15(2024), 1 vom: 17. Jan., Seite 11 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Jia, Ziqi [VerfasserIn] |
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| Links: |
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| Themen: |
Dual-layer spectral detector CT |
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| Anmerkungen: |
Date Revised 19.01.2024 published: Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1186/s13244-023-01593-5 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM367194562 |
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| 100 | 1 | |a Jia, Ziqi |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Performance of dual-layer spectrum CT virtual monoenergetic images to assess early rectal adenocarcinoma T-stage |b comparison with MR |
| 264 | 1 | |c 2024 | |
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| 500 | |a published: Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © 2024. The Author(s). | ||
| 520 | |a OBJECTIVES: To evaluate the image quality and utility of virtual monoenergetic images (VMI) of dual-layer spectrum computed tomography (DLSCT) in assessing preoperative T-stage for early rectal adenocarcinoma (ERA) | ||
| 520 | |a METHODS: This retrospective study included 67 ERA patients (mean age 62 ± 11.1 years) who underwent DLSCT and MR examination. VMI 40-200 keV and poly energetic image (PEI) were reconstructed. The image noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and tumor contrast of different energy levels were calculated and compared, respectively. Two radiologists independently assess the image quality of the VMIs and PEI using 5-point scales. The diagnostic accuracies of DLSCT and HR-MRI for ERA T-staging were evaluated and compared | ||
| 520 | |a RESULTS: The maximum noise was observed at VMI 40 keV, and noise at VMI 40-200 keV in the arterial and venous phases showed no significant difference (all p > 0.05). The highest SNR and CNR were obtained at VMI 40 keV, significantly greater than other energy levels and PEI (all p < 0.05). Tumor contrast was more evident than PEI at 40-100 keV in the arterial phase and at 40 keV in the venous phase (all p < 0.05). When compared with PEI, VMI 40 keV yielded the highest scores for overall image quality, tumor visibility, and tumor margin delineation, especially in the venous phase (p < 0.05). The overall diagnostic accuracy of DLSCT and HR-MRI for T-stage was 65.67 and 71.64% and showed no significant difference (p > 0.05) | ||
| 520 | |a CONCLUSIONS: VMI 40 keV improves image quality and accuracy in identifying lesions, providing better diagnostic information for ERA staging | ||
| 520 | |a CRITICAL RELEVANCE STATEMENT: Low-keV VMI from DLSCT can improve tumor staging accuracy for early rectal carcinoma, helping guide surgical intervention decisions, and has shed new light on the potential breakthroughs of assessing preoperative T-stage in RC | ||
| 520 | |a KEYPOINTS: • Compared with PEI, low-keV VIM derived from DLSCT, particularly at the 40 keV, significantly enhanced the objective and subjective image quality of ERA. • Using VMI 40 keV helped increase lesion detectability, leading to improved diagnostic accuracy for ERA. • Low-keV VMI from DLSCT has shed new light on the potential breakthroughs of assessing preoperative T-stage in RC | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Dual-layer spectral detector CT | |
| 650 | 4 | |a Early rectal adenocarcinoma | |
| 650 | 4 | |a Magnetic resonance imaging | |
| 650 | 4 | |a Tumor staging | |
| 650 | 4 | |a Virtual monochromatic imaging | |
| 700 | 1 | |a Guo, Lei |e verfasserin |4 aut | |
| 700 | 1 | |a Yuan, WenJing |e verfasserin |4 aut | |
| 700 | 1 | |a Dai, JianHao |e verfasserin |4 aut | |
| 700 | 1 | |a Lu, JianYe |e verfasserin |4 aut | |
| 700 | 1 | |a Li, ZhiQiang |e verfasserin |4 aut | |
| 700 | 1 | |a Du, Xiaohua |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Weicui |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Xian |e verfasserin |4 aut | |
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