Effect of antihypertensive treatment on the quality of life of patients with chronic rhinosinusitis with nasal polyps
Copyright © 2023 Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. Published by Elsevier España, S.L.U. All rights reserved..
AIM: Nasal polyposis (CRSwNP) shares type 2 inflammation biomarkers with asthma, allergy or arterial hypertension (AH), including periostin, a predictive marker of severity and post-surgical recurrence of polyposis. Antihypertensives have been shown to decrease periostin expression. We set out to evaluate the effect of antihypertensives on the quality of life of patients with CRSwNP.
MATERIALS AND METHODS: Retrospective study of 43 patients with CRSwNP and ah with at least 1 year of follow-up and antihypertensive treatment prescribed after the diagnosis of CRSwNP. Phenotypes were analyzed (F1: isolated CRSwNP; F2: CRSwNP with asthma and/or NERD) and aspects related to quality of life (SNOT-22), clinical severity (VAS), polypoid size (NPS), exacerbations and surgical needs after the initiation of antihypertensive treatment.
RESULTS: The predominant phenotype was F1 (62.8%). The number of exacerbations was 19.2% for F1, compared to 31.3% for F2. 34.8% underwent surgery after the start of antihypertensive treatment (F1 = 27.9% and F2 = 6.97%). A significant reduction in polypoid size, SNOT22 (16.4 ± 19.6 points), and VAS scales (p < .05) was obtained.
CONCLUSIONS: polypoid size, and reduce the risk of postoperative recurrence.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Acta otorrinolaringologica espanola - (2024) vom: 14. Jan. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Maza-Solano, Juan [VerfasserIn] |
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| Links: |
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| Themen: |
Arterial hypertension |
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| Anmerkungen: |
Date Revised 19.01.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1016/j.otoeng.2024.01.003 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM367105985 |
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| 520 | |a Copyright © 2023 Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. Published by Elsevier España, S.L.U. All rights reserved. | ||
| 520 | |a AIM: Nasal polyposis (CRSwNP) shares type 2 inflammation biomarkers with asthma, allergy or arterial hypertension (AH), including periostin, a predictive marker of severity and post-surgical recurrence of polyposis. Antihypertensives have been shown to decrease periostin expression. We set out to evaluate the effect of antihypertensives on the quality of life of patients with CRSwNP | ||
| 520 | |a MATERIALS AND METHODS: Retrospective study of 43 patients with CRSwNP and ah with at least 1 year of follow-up and antihypertensive treatment prescribed after the diagnosis of CRSwNP. Phenotypes were analyzed (F1: isolated CRSwNP; F2: CRSwNP with asthma and/or NERD) and aspects related to quality of life (SNOT-22), clinical severity (VAS), polypoid size (NPS), exacerbations and surgical needs after the initiation of antihypertensive treatment | ||
| 520 | |a RESULTS: The predominant phenotype was F1 (62.8%). The number of exacerbations was 19.2% for F1, compared to 31.3% for F2. 34.8% underwent surgery after the start of antihypertensive treatment (F1 = 27.9% and F2 = 6.97%). A significant reduction in polypoid size, SNOT22 (16.4 ± 19.6 points), and VAS scales (p < .05) was obtained | ||
| 520 | |a CONCLUSIONS: polypoid size, and reduce the risk of postoperative recurrence | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Arterial hypertension | |
| 650 | 4 | |a Calidad de vida | |
| 650 | 4 | |a Hipertensión arterial | |
| 650 | 4 | |a Nasal polyposis | |
| 650 | 4 | |a Periostin | |
| 650 | 4 | |a Periostina | |
| 650 | 4 | |a Poliposis nasal | |
| 650 | 4 | |a Quality of life | |
| 650 | 4 | |a SNOT22 | |
| 700 | 1 | |a Palma-Martínez, Carmen |e verfasserin |4 aut | |
| 700 | 1 | |a Martín-Jiménez, Daniel |e verfasserin |4 aut | |
| 700 | 1 | |a Sánchez-Gómez, Serafín |e verfasserin |4 aut | |
| 700 | 1 | |a Moreno-Luna, Ramón |e verfasserin |4 aut | |
| 700 | 1 | |a Calvo-Henriquez, Christian |e verfasserin |4 aut | |
| 700 | 1 | |a Galera-Ruiz, Hugo |e verfasserin |4 aut | |
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