Low-Temperature Adaptive Single-Atom Iron Nanozymes against Viruses in the Cold Chain
© 2024 Wiley‐VCH GmbH..
Outbreaks of viral infectious diseases, such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A virus (IAV), pose a great threat to human health. Viral spread is accelerated worldwide by the development of cold chain logistics; Therefore, an effective antiviral approach is required. In this study, it is aimed to develop a distinct antiviral strategy using nanozymes with low-temperature adaptability, suitable for cold chain logistics. Phosphorus (P) atoms are added to the remote counter position of Fe-N-C center to prepare FeN4P2-single-atom nanozymes (SAzymes), exhibiting lipid oxidase (OXD)-like activity at cold chain temperatures (-20, and 4 °C). This feature enables FeN4P2-SAzymes to disrupt multiple enveloped viruses (human, swine, and avian coronaviruses, and H1-H11 subtypes of IAV) by catalyzing lipid peroxidation of the viral lipid envelope. Under the simulated conditions of cold chain logistics, FeN4P2-SAzymes are successfully applied as antiviral coatings on outer packaging and personal protective equipment; Therefore, FeN4P2-SAzymes with low-temperature adaptability and broad-spectrum antiviral properties may serve as key materials for developing specific antiviral approaches to interrupt viral transmission through the cold chain.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:36 |
|---|---|
| Enthalten in: |
Advanced materials (Deerfield Beach, Fla.) - 36(2024), 15 vom: 15. Apr., Seite e2309669 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Qin, Tao [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Antiviral |
|---|
| Anmerkungen: |
Date Completed 15.04.2024 Date Revised 15.04.2024 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1002/adma.202309669 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM367067021 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM367067021 | ||
| 003 | DE-627 | ||
| 005 | 20240415233109.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240114s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/adma.202309669 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1376.xml |
| 035 | |a (DE-627)NLM367067021 | ||
| 035 | |a (NLM)38216154 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Qin, Tao |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Low-Temperature Adaptive Single-Atom Iron Nanozymes against Viruses in the Cold Chain |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 15.04.2024 | ||
| 500 | |a Date Revised 15.04.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2024 Wiley‐VCH GmbH. | ||
| 520 | |a Outbreaks of viral infectious diseases, such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A virus (IAV), pose a great threat to human health. Viral spread is accelerated worldwide by the development of cold chain logistics; Therefore, an effective antiviral approach is required. In this study, it is aimed to develop a distinct antiviral strategy using nanozymes with low-temperature adaptability, suitable for cold chain logistics. Phosphorus (P) atoms are added to the remote counter position of Fe-N-C center to prepare FeN4P2-single-atom nanozymes (SAzymes), exhibiting lipid oxidase (OXD)-like activity at cold chain temperatures (-20, and 4 °C). This feature enables FeN4P2-SAzymes to disrupt multiple enveloped viruses (human, swine, and avian coronaviruses, and H1-H11 subtypes of IAV) by catalyzing lipid peroxidation of the viral lipid envelope. Under the simulated conditions of cold chain logistics, FeN4P2-SAzymes are successfully applied as antiviral coatings on outer packaging and personal protective equipment; Therefore, FeN4P2-SAzymes with low-temperature adaptability and broad-spectrum antiviral properties may serve as key materials for developing specific antiviral approaches to interrupt viral transmission through the cold chain | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a antiviral | |
| 650 | 4 | |a broad‐spectrum | |
| 650 | 4 | |a cold chain | |
| 650 | 4 | |a low temperature adaptability | |
| 650 | 4 | |a single‐atom nanozymes | |
| 650 | 7 | |a Iron |2 NLM | |
| 650 | 7 | |a E1UOL152H7 |2 NLM | |
| 650 | 7 | |a Antiviral Agents |2 NLM | |
| 650 | 7 | |a Lipids |2 NLM | |
| 700 | 1 | |a Chen, Yulian |e verfasserin |4 aut | |
| 700 | 1 | |a Miao, Xinyu |e verfasserin |4 aut | |
| 700 | 1 | |a Shao, Mengjuan |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Nuo |e verfasserin |4 aut | |
| 700 | 1 | |a Mou, Chunxiao |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Zhenhai |e verfasserin |4 aut | |
| 700 | 1 | |a Yin, Yuncong |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Sujuan |e verfasserin |4 aut | |
| 700 | 1 | |a Yin, Yinyan |e verfasserin |4 aut | |
| 700 | 1 | |a Gao, Lizeng |e verfasserin |4 aut | |
| 700 | 1 | |a Peng, Daxin |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Xiufan |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Advanced materials (Deerfield Beach, Fla.) |d 1998 |g 36(2024), 15 vom: 15. Apr., Seite e2309669 |w (DE-627)NLM098206397 |x 1521-4095 |7 nnns |
| 773 | 1 | 8 | |g volume:36 |g year:2024 |g number:15 |g day:15 |g month:04 |g pages:e2309669 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1002/adma.202309669 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 36 |j 2024 |e 15 |b 15 |c 04 |h e2309669 | ||