Targeting Protein Phosphatases for the Treatment of Chronic Liver Disease

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There exists a huge number of patients suffering from chronic liver disease worldwide. As a disease with high incidence and mortality worldwide, strengthening the research on the pathogenesis of chronic liver disease and the development of novel drugs is an important issue related to the health of all human beings. Phosphorylation modification of proteins plays a crucial role in cellular signal transduction, and phosphatases are involved in the development of liver diseases. Therefore, this article summarized the important role of protein phosphatases in chronic liver disease with the aim of facilitating the development of drugs targeting protein phosphatases for the treatment of chronic liver disease.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Current drug targets - (2024) vom: 11. Jan.

Sprache:

Englisch

Beteiligte Personen:

Li, Yi-Ming [VerfasserIn]
He, Hong-Wei [VerfasserIn]
Zhang, Na [VerfasserIn]

Links:

Volltext

Themen:

Chronic liver disease
Drug discovery
Hepatocellular carcinoma
Journal Article
Liver fibrosis
Non-alcoholic fatty liver disease
Phosphoprotein phosphatases
Target identification

Anmerkungen:

Date Revised 12.01.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.2174/0113894501278886231221092522

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM367037157