Continuous erector spinae plane block versus thoracic epidural analgesia in video-assisted thoracoscopic surgery : a prospective randomized open-label non-inferiority trial
© American Society of Regional Anesthesia & Pain Medicine 2024. No commercial re-use. See rights and permissions. Published by BMJ..
BACKGROUND AND OBJECTIVES: The evolving surgical techniques in thoracoscopic surgery necessitate the exploration of anesthesiological techniques. This study aimed to investigate whether incorporating a continuous erector spinae plane (ESP) block into a multimodal analgesia regimen is non-inferior to continuous thoracic epidural analgesia (TEA) in terms of quality of postoperative recovery for patients undergoing elective unilateral video-assisted thoracoscopic surgery.
METHODS: We conducted a multicenter, prospective, randomized, open-label non-inferiority trial between July 2020 and December 2022. Ninety patients were randomly assigned to receive either continuous ESP block or TEA. The primary outcome parameter was the Quality of Recovery-15 (QoR-15) score, measured before surgery as a baseline and on postoperative days 0, 1, and 2. Secondary outcome parameters included pain scores, length of hospital stay, morphine consumption, nausea and vomiting, itching, speed of mobilization, and urinary catheterization.
RESULTS: Analysis of the primary outcome showed a mean QoR-15 difference between the groups ESP block versus TEA of 1 (95% CI -9 to -12, p=0.79) on day 0, -1 (95% CI -11 to -8, p=0.81) on day 1 and -2 (95% CI -14 to -11, p=0.79) on day 2.
CONCLUSIONS: The continuous ESP block is non-inferior to TEA in video-assisted thoracoscopic surgery.
TRIAL REGISTRATION NUMBER: Dutch Trial Register (NL6433).
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Regional anesthesia and pain medicine - (2024) vom: 11. Jan. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
van den Broek, Renee J C [VerfasserIn] |
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| Links: |
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| Themen: |
Analgesia |
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| Anmerkungen: |
Date Revised 11.01.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1136/rapm-2023-105047 |
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| Förderinstitution / Projekttitel: |
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| 520 | |a © American Society of Regional Anesthesia & Pain Medicine 2024. No commercial re-use. See rights and permissions. Published by BMJ. | ||
| 520 | |a BACKGROUND AND OBJECTIVES: The evolving surgical techniques in thoracoscopic surgery necessitate the exploration of anesthesiological techniques. This study aimed to investigate whether incorporating a continuous erector spinae plane (ESP) block into a multimodal analgesia regimen is non-inferior to continuous thoracic epidural analgesia (TEA) in terms of quality of postoperative recovery for patients undergoing elective unilateral video-assisted thoracoscopic surgery | ||
| 520 | |a METHODS: We conducted a multicenter, prospective, randomized, open-label non-inferiority trial between July 2020 and December 2022. Ninety patients were randomly assigned to receive either continuous ESP block or TEA. The primary outcome parameter was the Quality of Recovery-15 (QoR-15) score, measured before surgery as a baseline and on postoperative days 0, 1, and 2. Secondary outcome parameters included pain scores, length of hospital stay, morphine consumption, nausea and vomiting, itching, speed of mobilization, and urinary catheterization | ||
| 520 | |a RESULTS: Analysis of the primary outcome showed a mean QoR-15 difference between the groups ESP block versus TEA of 1 (95% CI -9 to -12, p=0.79) on day 0, -1 (95% CI -11 to -8, p=0.81) on day 1 and -2 (95% CI -14 to -11, p=0.79) on day 2 | ||
| 520 | |a CONCLUSIONS: The continuous ESP block is non-inferior to TEA in video-assisted thoracoscopic surgery | ||
| 520 | |a TRIAL REGISTRATION NUMBER: Dutch Trial Register (NL6433) | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Pain Management | |
| 650 | 4 | |a Postoperative Pain | |
| 650 | 4 | |a REGIONAL ANESTHESIA | |
| 650 | 4 | |a Treatment Outcome | |
| 650 | 4 | |a analgesia | |
| 700 | 1 | |a Postema, Jonne M C |e verfasserin |4 aut | |
| 700 | 1 | |a Koopman, Joseph S H A |e verfasserin |4 aut | |
| 700 | 1 | |a van Rossem, Charles C |e verfasserin |4 aut | |
| 700 | 1 | |a Olsthoorn, Jules R |e verfasserin |4 aut | |
| 700 | 1 | |a van Brakel, Thomas J |e verfasserin |4 aut | |
| 700 | 1 | |a Houterman, Saskia |e verfasserin |4 aut | |
| 700 | 1 | |a Bouwman, R Arthur |e verfasserin |4 aut | |
| 700 | 1 | |a Versyck, Barbara |e verfasserin |4 aut | |
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