A kV-MV approach to CBCT metal artifact reduction using multi-layer MV-CBCT
© 2024 Institute of Physics and Engineering in Medicine..
Objective. To demonstrate that complete cone beam CT (CBCT) scans from both MV-energy and kV-energy LINAC sources can reduce metal artifacts in radiotherapy guidance, while maintaining standard-of-care x-ray doses levels.Approach. MV-CBCT and kV-CBCT scans are acquired at half normal dose. The impact of lowered dose on MV-CBCT data quality is mitigated by the use of a 4-layer MV-imager prototype and reduced LINAC energy settings (2.5 MV) to improve photon capture. Additionally, the MV-CBCT is used to determine the 3D position and pose of metal implants, which in turn is used to guide model-based poly-energetic correction and interleaving of the kV-CBCT and MV-CBCT data. Certain edge-preserving regularization steps incorporated into the model-based correction algorithm further reduce MV data noise.Main results. The method was tested in digital phantoms and a real pelvis phantom with large 2.5″ spherical inserts, emulating hip replacements of different materials. The proposed method demonstrated an appealing compromise between the high contrast of kV-CBCT and low artifact content of MV-CBCT. Contrast-to-noise improved 3-fold compared to MV-CBCT with a clinical 1-layer architecture at matched dose (37 mGy) and edge blur levels. Visual delineation of the bladder and prostate improved noteably over kV- or MV-CBCT alone.Significance. The proposed method demonstrates that a full MV-CBCT scan can be combined with kV-CBCT to reduce metal artifacts without resorting to complicated beam collimation strategies to limit the MV-CBCT dose contribution. Additionally, significant improvements in CNR can be achieved as compared to metal artifact reduction through current clinical MV-CBCT practices.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:69 |
|---|---|
| Enthalten in: |
Physics in medicine and biology - 69(2024), 7 vom: 14. März |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Jacobson, Matthew W [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Cone beam CT |
|---|
| Anmerkungen: |
Date Completed 15.03.2024 Date Revised 09.04.2024 published: Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1088/1361-6560/ad1cfb |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM366893181 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM366893181 | ||
| 003 | DE-627 | ||
| 005 | 20240409232329.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240114s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1088/1361-6560/ad1cfb |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1370.xml |
| 035 | |a (DE-627)NLM366893181 | ||
| 035 | |a (NLM)38198730 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Jacobson, Matthew W |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A kV-MV approach to CBCT metal artifact reduction using multi-layer MV-CBCT |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 15.03.2024 | ||
| 500 | |a Date Revised 09.04.2024 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2024 Institute of Physics and Engineering in Medicine. | ||
| 520 | |a Objective. To demonstrate that complete cone beam CT (CBCT) scans from both MV-energy and kV-energy LINAC sources can reduce metal artifacts in radiotherapy guidance, while maintaining standard-of-care x-ray doses levels.Approach. MV-CBCT and kV-CBCT scans are acquired at half normal dose. The impact of lowered dose on MV-CBCT data quality is mitigated by the use of a 4-layer MV-imager prototype and reduced LINAC energy settings (2.5 MV) to improve photon capture. Additionally, the MV-CBCT is used to determine the 3D position and pose of metal implants, which in turn is used to guide model-based poly-energetic correction and interleaving of the kV-CBCT and MV-CBCT data. Certain edge-preserving regularization steps incorporated into the model-based correction algorithm further reduce MV data noise.Main results. The method was tested in digital phantoms and a real pelvis phantom with large 2.5″ spherical inserts, emulating hip replacements of different materials. The proposed method demonstrated an appealing compromise between the high contrast of kV-CBCT and low artifact content of MV-CBCT. Contrast-to-noise improved 3-fold compared to MV-CBCT with a clinical 1-layer architecture at matched dose (37 mGy) and edge blur levels. Visual delineation of the bladder and prostate improved noteably over kV- or MV-CBCT alone.Significance. The proposed method demonstrates that a full MV-CBCT scan can be combined with kV-CBCT to reduce metal artifacts without resorting to complicated beam collimation strategies to limit the MV-CBCT dose contribution. Additionally, significant improvements in CNR can be achieved as compared to metal artifact reduction through current clinical MV-CBCT practices | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a cone beam CT | |
| 650 | 4 | |a image guidance | |
| 650 | 4 | |a metal artifacts | |
| 650 | 4 | |a multi-layer detector | |
| 650 | 4 | |a radiation therapy | |
| 650 | 4 | |a radiotherapy | |
| 700 | 1 | |a Harris, Tom |e verfasserin |4 aut | |
| 700 | 1 | |a Myronakis, Marios |e verfasserin |4 aut | |
| 700 | 1 | |a Lehmann, Mathias |e verfasserin |4 aut | |
| 700 | 1 | |a Huber, Pascal |e verfasserin |4 aut | |
| 700 | 1 | |a Ozoemelam, Ikechi |e verfasserin |4 aut | |
| 700 | 1 | |a Hu, Yue-Houng |e verfasserin |4 aut | |
| 700 | 1 | |a Ferguson, Dianne |e verfasserin |4 aut | |
| 700 | 1 | |a Fueglistaller, Rony |e verfasserin |4 aut | |
| 700 | 1 | |a Morf, Daniel |e verfasserin |4 aut | |
| 700 | 1 | |a Berbeco, Ross |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Physics in medicine and biology |d 1956 |g 69(2024), 7 vom: 14. März |w (DE-627)NLM000336505 |x 1361-6560 |7 nnns |
| 773 | 1 | 8 | |g volume:69 |g year:2024 |g number:7 |g day:14 |g month:03 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1088/1361-6560/ad1cfb |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 69 |j 2024 |e 7 |b 14 |c 03 | ||