Optimizing CO2 field flooding during sternotomy : In vitro confirmation of the Karolinska studies

Copyright: © 2024 Puthettu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited..

Although CO2 field-flooding was first used during cardiac surgery more than 60 years ago, its efficacy is still disputed. The invisible nature of the gas and the difficulty in determining the "safe" quantity to protect the patient are two of the main obstacles to overcome for its validation. Moreover, CO2 concentration in the chest cavity is highly sensitive to procedural aspects, such suction and hand movements. Based on our review of the existing literature, we identified four major factors that influence the intra-cavity CO2 concentration during open-heart surgery: type of delivery device (diffuser), delivery CO2 flow rate, diffuser position around the wound cavity, and its orientation inside the cavity. In this initial study, only steady state conditions were considered to establish a basic understanding on the effect of the four above-mentioned factors. Transient factors, such as suction or hand movements, will be reported separately.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:19

Enthalten in:

PloS one - 19(2024), 1 vom: 31., Seite e0292669

Sprache:

Englisch

Beteiligte Personen:

Puthettu, Mira [VerfasserIn]
Vandenberghe, Stijn [VerfasserIn]
Balafas, Spyros [VerfasserIn]
Di Serio, Clelia [VerfasserIn]
Singjeli, Geni [VerfasserIn]
Pagnamenta, Alberto [VerfasserIn]
Demertzis, Stefanos [VerfasserIn]

Links:

Volltext

Themen:

142M471B3J
Carbon Dioxide
Journal Article
Review

Anmerkungen:

Date Completed 11.01.2024

Date Revised 11.01.2024

published: Electronic-eCollection

Citation Status MEDLINE

doi:

10.1371/journal.pone.0292669

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM366850288