Association between periodontal disease and malignant soft tissue sarcomas
© 2024 Wiley Periodicals LLC..
OBJECTIVE: Malignant soft tissue sarcoma (MSTS) is a rare disease, but is seen in patients undergoing orthopedic surgery. Although the association of periodontal disease with various cancers occurring in the oral cavity, gastrointestinal tract, lungs, and prostate, has been reported, the association between periodontal disease and MSTS remains unclear. This study investigated the association between periodontal disease and MSTS in patients undergoing orthopedic surgery.
SUBJECTS AND METHODS: One hundred fifteen patients who underwent orthopedic surgery between 2017 and 2021 were retrospectively enrolled (mean age = 66.8 ± 10.7 years). The patient background was adjusted by the propensity score (PS). Subsequently, the association of periodontal disease with MSTS was analyzed using PS inverse probability of treatment weighting (IPTW). Periodontal status was determined by evaluating the periodontal inflamed surface area, which was calculated by measuring the periodontal probing pocket depth and detecting bleeding on probing.
RESULTS: Multivariate logistic regression analysis after adjustment by the PS showed that severe periodontitis was significantly associated with MSTS (odds ratio 2.81, p = 0.04). Furthermore, IPTW showed that severe periodontitis was significantly associated with MSTS (odds ratio 3.21, p = 0.01).
CONCLUSION: The results indicate an association between periodontal inflammation and MSTS.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Oral diseases - (2024) vom: 08. Jan. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Hiroshimaya, Takatoshi [VerfasserIn] |
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| Links: |
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| Themen: |
Journal Article |
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| Anmerkungen: |
Date Revised 09.01.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1111/odi.14853 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM366824228 |
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| 100 | 1 | |a Hiroshimaya, Takatoshi |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Association between periodontal disease and malignant soft tissue sarcomas |
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| 500 | |a Date Revised 09.01.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a © 2024 Wiley Periodicals LLC. | ||
| 520 | |a OBJECTIVE: Malignant soft tissue sarcoma (MSTS) is a rare disease, but is seen in patients undergoing orthopedic surgery. Although the association of periodontal disease with various cancers occurring in the oral cavity, gastrointestinal tract, lungs, and prostate, has been reported, the association between periodontal disease and MSTS remains unclear. This study investigated the association between periodontal disease and MSTS in patients undergoing orthopedic surgery | ||
| 520 | |a SUBJECTS AND METHODS: One hundred fifteen patients who underwent orthopedic surgery between 2017 and 2021 were retrospectively enrolled (mean age = 66.8 ± 10.7 years). The patient background was adjusted by the propensity score (PS). Subsequently, the association of periodontal disease with MSTS was analyzed using PS inverse probability of treatment weighting (IPTW). Periodontal status was determined by evaluating the periodontal inflamed surface area, which was calculated by measuring the periodontal probing pocket depth and detecting bleeding on probing | ||
| 520 | |a RESULTS: Multivariate logistic regression analysis after adjustment by the PS showed that severe periodontitis was significantly associated with MSTS (odds ratio 2.81, p = 0.04). Furthermore, IPTW showed that severe periodontitis was significantly associated with MSTS (odds ratio 3.21, p = 0.01) | ||
| 520 | |a CONCLUSION: The results indicate an association between periodontal inflammation and MSTS | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a malignant soft tissue sarcoma | |
| 650 | 4 | |a periodontal disease | |
| 650 | 4 | |a periodontal inflamed surface area | |
| 650 | 4 | |a propensity score | |
| 700 | 1 | |a Fujimoto, Yusuke |e verfasserin |4 aut | |
| 700 | 1 | |a Sasaki, Hiromi |e verfasserin |4 aut | |
| 700 | 1 | |a Motoi, Toshihiro |e verfasserin |4 aut | |
| 700 | 1 | |a Nagata, Emi |e verfasserin |4 aut | |
| 700 | 1 | |a Taniguchi, Noboru |e verfasserin |4 aut | |
| 700 | 1 | |a Oho, Takahiko |e verfasserin |4 aut | |
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