Carbon Nanotubes for Targeted Therapy : Safety, Efficacy, Feasibility and Regulatory Aspects

Copyright© Bentham Science Publishers; For any queries, please email at epubbenthamscience.net..

It is crucial that novel and efficient drug delivery techniques be created in order to improve the pharmacological profiles of a wide variety of classes of medicinal compounds. Carbon nanotubes (CNTs) have recently come to the forefront as an innovative and very effective technique for transporting and translocating medicinal compounds. CNTs were suggested and aggressively researched as multifunctional novel transporters designed for targeted pharmaceutical distribution and used in diagnosis. CNTs can act as vectors for direct administration of pharmaceuticals, particularly chemotherapeutic medications. Multi-walled CNTs make up the great majority of CNT transporters, and these CNTs were used in techniques to target cancerous cells. It is possible to employ Carbon nanotubes (CNTs) to transport bioactive peptides, proteins, nucleic acids, and medicines by functionalizing them with these substances. Due to their low toxicity and absence of immunogenicity, carbon nanotubes are not immunogenic. Ammonium-functionalized carbon nanotubes are also attractive vectors for gene-encoding nucleic acids. CNTs that have been coupled with antigenic peptides have the potential to be developed into a novel and efficient approach for the use of synthetic vaccines. CNTs bring up an enormous number of new avenues for future medicine development depending on targets within cells, which have until now been difficult to access. This review focuses on the numerous applications of various CNT types used as medicine transport systems and on the utilization of CNTs for therapeutical purposes.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:30

Enthalten in:

Current pharmaceutical design - 30(2024), 2 vom: 07., Seite 81-99

Sprache:

Englisch

Beteiligte Personen:

Gupta, Babita [VerfasserIn]
Sharma, Pramod Kumar [VerfasserIn]
Malviya, Rishabha [VerfasserIn]

Links:

Volltext

Themen:

Carbon nanotube
Chemotherapeutic medications.
Drug delivery
Journal Article
Nanotubes, Carbon
Nucleic Acids
Patient care
Peptides
Review
Targeted delivery
Toxicity

Anmerkungen:

Date Completed 28.03.2024

Date Revised 08.04.2024

published: Print

Citation Status MEDLINE

doi:

10.2174/0113816128282085231226065407

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM366765116