Ninety-eight semesters of cytochrome P450 enzymes and related topics-What have I taught and learned?

Copyright © 2024 The Author. Published by Elsevier Inc. All rights reserved..

This Reflection article begins with my family background and traces my career through elementary and high school, followed by time at the University of Illinois, Vanderbilt University, the University of Michigan, and then for 98 semesters as a Vanderbilt University faculty member. My research career has dealt with aspects of cytochrome P450 enzymes, and the basic biochemistry has had applications in fields as diverse as drug metabolism, toxicology, medicinal chemistry, pharmacogenetics, biological engineering, and bioremediation. I am grateful for the opportunity to work with the Journal of Biological Chemistry not only as an author but also for 34 years as an Editorial Board Member, Associate Editor, Deputy Editor, and interim Editor-in-Chief. Thanks are extended to my family and my mentors, particularly Profs. Harry Broquist and Minor J. Coon, and the more than 170 people who have trained with me. I have never lost the enthusiasm for research that I learned in the summer of 1968 with Harry Broquist, and I have tried to instill this in the many trainees I have worked with. A sentence I use on closing slides is "It's not just a laboratory-it's a fraternity.".

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:300

Enthalten in:

The Journal of biological chemistry - 300(2024), 2 vom: 15. Feb., Seite 105625

Sprache:

Englisch

Beteiligte Personen:

Guengerich, F Peter [VerfasserIn]

Links:

Volltext

Themen:

9035-51-2
Cytochrome P-450 Enzyme System
Cytochrome P450
Electron transfer
Enzyme kinetics
Enzyme mechanisms
Journal Article
Mentoring
Oxidation-reduction
Steroid metabolism
Toxicology drug metabolism

Anmerkungen:

Date Completed 26.02.2024

Date Revised 27.02.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.jbc.2024.105625

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM366758675