A Successfully Treated COVID-19 Vaccine Induced Immune Thrombocytopenic Purpura

Copyright © 2023, Rodriguez Guerra et al..

Immune Thrombocytopenic Purpura (ITP) is a life-threatening condition where an accurate initial assessment is essential to be able to offer the proper therapy in a timely matter to improve the outcome of the patient. Here, we present a case of ITP secondary to the coronavirus disease 2019 (COVID-19) vaccine (BioNTech, Pfizer vaccine). A 61-year-old obese African American female presented to the emergency room (ER) from a clinic with a platelet count of 11k/ul 21 days after she received the second dose of the BioNTech, Pfizer vaccine. The patient was immediately started on intravenous immunoglobulin (IVIG) 1g/kg twice daily (bid) and dexamethasone 20 mg IV every 12 hrs (q12h). The next day, the platelet count increased to 63 k/ul, and after the second dose of IVIG, the platelet count improved to 122 k/ul and trended up. The early detection of ITP induced by the mRNA COVID-19 vaccine is determinant to guide the early and proper therapy with immunoglobulins and steroids to improve the outcome of our patients.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:15

Enthalten in:

Cureus - 15(2023), 12 vom: 18. Dez., Seite e49878

Sprache:

Englisch

Beteiligte Personen:

Rodriguez Guerra, Miguel A [VerfasserIn]
Chinta, Siddharth [VerfasserIn]
Urena Neme, Ana P [VerfasserIn]
Gupta, Sorab [VerfasserIn]
Roa Gomez, Gabriella [VerfasserIn]

Links:

Volltext

Themen:

Bnt162b2 vaccine
Case Reports
Covid 19
Intravenous immunoglobulin (ivig)
Mrna covid-19 vaccine
Vaccine induced immune thrombocytopenia

Anmerkungen:

Date Revised 05.01.2024

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.7759/cureus.49878

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM366647792