Effective Management of Hypertensive Emergencies with Aliskiren Treatment in a Patient Before and After Introducing Hemodialysis Secondary to Scleroderma Renal Crisis-like Condition Under Corticosteroid Treatment for Sjögren Syndrome-associated Multiple Mononeuropathy
A middle-aged woman presented with hypertensive emergency after corticosteroid treatment for Sjögren syndrome-associated multiple mononeuropathy with suspected systemic sclerosis. Hypertensive heart failure with hyperreninemia improved with antihypertensives, including aliskiren; however, she became hemodialysis-dependent. Clinical findings and biopsy-proven thrombotic microangiopathy indicated conditions resembling scleroderma renal crisis (SRC). Severe hypertension and heart failure with hyperreninemia occurred after stopping aliskiren for hypotension due to diverticular bleeding, which improved after the reintroduction of aliskiren. Aliskiren appears to be effective in managing hypertensive heart failure in patients with SRC. Nevertheless, hemodialysis remained necessary in our case, and whether or not aliskiren can restore the renal function is unclear.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Internal medicine (Tokyo, Japan) - (2024) vom: 02. Jan. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yamazaki, Osamu [VerfasserIn] |
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| Links: |
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| Themen: |
Aliskiren |
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| Anmerkungen: |
Date Revised 03.01.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.2169/internalmedicine.2970-23 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM366624857 |
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| 245 | 1 | 0 | |a Effective Management of Hypertensive Emergencies with Aliskiren Treatment in a Patient Before and After Introducing Hemodialysis Secondary to Scleroderma Renal Crisis-like Condition Under Corticosteroid Treatment for Sjögren Syndrome-associated Multiple Mononeuropathy |
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| 500 | |a Date Revised 03.01.2024 | ||
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| 520 | |a A middle-aged woman presented with hypertensive emergency after corticosteroid treatment for Sjögren syndrome-associated multiple mononeuropathy with suspected systemic sclerosis. Hypertensive heart failure with hyperreninemia improved with antihypertensives, including aliskiren; however, she became hemodialysis-dependent. Clinical findings and biopsy-proven thrombotic microangiopathy indicated conditions resembling scleroderma renal crisis (SRC). Severe hypertension and heart failure with hyperreninemia occurred after stopping aliskiren for hypotension due to diverticular bleeding, which improved after the reintroduction of aliskiren. Aliskiren appears to be effective in managing hypertensive heart failure in patients with SRC. Nevertheless, hemodialysis remained necessary in our case, and whether or not aliskiren can restore the renal function is unclear | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a aliskiren | |
| 650 | 4 | |a hyperreninemia | |
| 650 | 4 | |a hypertension | |
| 650 | 4 | |a multiple mononeuropathy | |
| 650 | 4 | |a scleroderma renal crisis | |
| 650 | 4 | |a thrombotic microangiopathy | |
| 700 | 1 | |a Murakawa, Masataka |e verfasserin |4 aut | |
| 700 | 1 | |a Ochiai, Fumika |e verfasserin |4 aut | |
| 700 | 1 | |a Fujii, Wataru |e verfasserin |4 aut | |
| 700 | 1 | |a Asakawa, Shinichiro |e verfasserin |4 aut | |
| 700 | 1 | |a Nagura, Michito |e verfasserin |4 aut | |
| 700 | 1 | |a Arai, Shigeyuki |e verfasserin |4 aut | |
| 700 | 1 | |a Tamura, Yoshifuru |e verfasserin |4 aut | |
| 700 | 1 | |a Ohashi, Ryuji |e verfasserin |4 aut | |
| 700 | 1 | |a Shibata, Shigeru |e verfasserin |4 aut | |
| 700 | 1 | |a Fujigaki, Yoshihide |e verfasserin |4 aut | |
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