SSC : The novel self-stack ensemble model for thyroid disease prediction

Copyright: © 2024 Shengjun Ji. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited..

Thyroid disease presents a significant health risk, lowering the quality of life and increasing treatment costs. The diagnosis of thyroid disease can be challenging, especially for inexperienced practitioners. Machine learning has been established as one of the methods for disease diagnosis based on previous studies. This research introduces a novel and more effective technique for predicting thyroid disease by utilizing machine learning methodologies, surpassing the performance of previous studies in this field. This study utilizes the UCI thyroid disease dataset, which consists of 9172 samples and 30 features, and exhibits a highly imbalanced target class distribution. However, machine learning algorithms trained on imbalanced thyroid disease data face challenges in reliably detecting minority data and disease. To address this issue, re-sampling is employed, which modifies the ratio between target classes to balance the data. In this study, the down-sampling approach is utilized to achieve a balanced distribution of target classes. A novel RF-based self-stacking classifier is presented in this research for efficient thyroid disease detection. The proposed approach demonstrates the ability to diagnose primary hypothyroidism, increased binding protein, compensated hypothyroidism, and concurrent non-thyroidal illness with an accuracy of 99.5%. The recommended model exhibits state-of-the-art performance, achieving 100% macro precision, 100% macro recall, and 100% macro F1-score. A thorough comparative assessment is conducted to demonstrate the viability of the proposed approach, including several machine learning classifiers, deep neural networks, and ensemble voting classifiers. The results of K-fold cross-validation provide further support for the efficacy of the proposed self-stacking classifier.

Medienart:	E-Artikel

Erscheinungsjahr:	2024
Erschienen:	2024

Enthalten in:	Zur Gesamtaufnahme - volume:19
Enthalten in:	PloS one - 19(2024), 1 vom: 31., Seite e0295501

Sprache:	Englisch

Beteiligte Personen:	Ji, Shengjun [VerfasserIn]

Links:	Volltext

Themen:	Journal Article

Anmerkungen:	Date Completed 05.01.2024 Date Revised 06.01.2024 published: Electronic-eCollection Citation Status MEDLINE

doi:	10.1371/journal.pone.0295501

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	NLM366613448